XXYLT1 Inhibitors
XXYLT1 Inhibitors are a class of compounds that can directly or indirectly decrease the functional activity of XXYLT1. XXYLT1 participates in various biological processes and is influenced by several signaling pathways. Staurosporine, a potent protein kinase C (PKC) inhibitor, can lead to decreased functional activity of XXYLT1, as PKC activation is involved in various cellular pathways that include signal transduction and cell growth. Genistein, a tyrosine kinase inhibitor, can inhibit XXYLT1 if its activity is mediated by tyrosine phosphorylation, as it blocks the phosphorylation process and prevents activation of associated signaling pathways.
The inhibitors LY294002 and Wortmannin target the phosphatidylinositol 3-kinase (PI3K) pathway, which has been shown to regulate numerous cellular processes. Their action can lead to decreased XXYLT1 activity by impairing downstream signaling pathways critical for XXYLT1 activity. Similarly, rapamycin, an mTOR inhibitor, can also impair XXYLT1 activity, as mTOR is a master regulator of cellular growth and metabolism. MEK inhibitors such as U0126, PD98059, Trametinib, and Selumetinib can lead to decreased XXYLT1 activity by inhibiting the ERK1/2 signaling pathway, which can impact XXYLT1 activity. Compounds like SB203580 and SP600125 inhibit the p38 MAPK and JNK pathways respectively, impairing the associated signaling pathways contributing to XXYLT1 activity. Lastly, BAY 11-7082, an inhibitor of NF-κB activation, can also impair the associated signaling pathways contributing to XXYLT1 activity, leading to decreased functional activity of XXYLT1.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine, a protein kinase C (PKC) inhibitor, could lead to decreased XXYLT1 activity. PKC is involved in various cellular pathways that include signal transduction and cell growth. By inhibiting PKC, the associated signaling pathways that contribute to XXYLT1 activity are impaired. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a tyrosine kinase inhibitor, can inhibit XXYLT1 if its activity is mediated by tyrosine phosphorylation. Genistein blocks the phosphorylation process, thereby preventing activation of signaling pathways associated with XXYLT1. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor. By blocking PI3K, it impairs downstream signaling pathways that may be critical for XXYLT1 activity, leading to decreased functional activity of XXYLT1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR, a master regulator of cellular growth and metabolism. By inhibiting mTOR, the associated signaling pathways that contribute to XXYLT1 activity are impaired, leading to decreased XXYLT1 activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a p38 MAPK inhibitor. By inhibiting p38 MAPK, the associated signaling pathways that contribute to XXYLT1 activity are impaired, leading to decreased functional activity of XXYLT1. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor. By inhibiting JNK, it can impair the JNK pathway, thereby potentially decreasing the functional activity of XXYLT1. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a MEK inhibitor. It inhibits the MAPK signaling pathway that could be involved in the regulation of XXYLT1, leading to decreased functional activity of XXYLT1. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a PI3K inhibitor. By inhibiting PI3K, it can impair downstream signaling pathways that may be critical for XXYLT1 activity, leading to decreased functional activity of XXYLT1. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
BAY 11-7082 inhibits NF-κB activation. By inhibiting this pathway, it can impair the associated signaling pathways contributing to XXYLT1 activity, thereby leading to decreased XXYLT1 activity. | ||||||
Trametinib | 871700-17-3 | sc-364639 sc-364639A sc-364639B | 5 mg 10 mg 1 g | $114.00 $166.00 $947.00 | 19 | |
Trametinib is a MEK inhibitor. By inhibiting MEK, it impairs the MAPK/ERK pathway which could be involved in the regulation of XXYLT1, leading to decreased functional activity of XXYLT1. | ||||||