Date published: 2025-10-7

1-800-457-3801

SCBT Portrait Logo
Seach Input

XBP Antibodies

Santa Cruz Biotechnology features a diverse variety of XBP Antibodies for advanced research in cellular stress responses and the unfolded protein response (UPR). XBP Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). XBP, or X-box binding protein, plays a central role in regulating gene expression during the UPR, which is essential for maintaining cellular homeostasis under stress conditions. The activation of XBP is crucial for proper protein folding and the overall health of the endoplasmic reticulum. Dysregulation of XBP has been linked to various diseases, including cancer and neurodegenerative disorders, making it significant in both basic and translational research. Understanding XBP function helps reveal key mechanisms in cellular stress pathways and protein quality control. Investigating XBP signaling pathways provides insights into potential therapeutic targets for various diseases. Research with XBP can enhance understanding of cellular adaptation to stress conditions. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific knowledge of cellular stress responses and therapeutic development.

SEE ALSO...

XBP Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

XBP1 Antibody (F-4)

sc-8015mouse IgG1 κ76-263 (m)WB, IP, IF, ELISAm, r, h
62
(27)

XBP CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

XBP1 CRISPR/Cas9 KO Plasmid (h2)

sc-400131-KO-2hGene KnockoutGFP0
(0)

XBP1 HDR Plasmid (h2)

sc-400131-HDR-2hHomology Directed RepairPuromycin0
(0)

XBP1 Double Nickase Plasmid (h)

sc-400131-NIChGene KnockoutPuromycin0
(0)

XBP1 Double Nickase Plasmid (h2)

sc-400131-NIC-2hGene KnockoutPuromycin0
(0)

XBP1 CRISPR/Cas9 KO Plasmid (m)

sc-423727mGene KnockoutGFP0
(2)

XBP1 HDR Plasmid (m)

sc-423727-HDRmHomology Directed RepairPuromycin0
(2)

XBP1 Double Nickase Plasmid (m)

sc-423727-NICmGene KnockoutPuromycin0
(2)

XBP1 Double Nickase Plasmid (m2)

sc-423727-NIC-2mGene KnockoutPuromycin0
(2)

XBP CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

XBP1 CRISPR Activation Plasmid (h)

sc-400131-ACThGene ActivationPuro, Blast, Hygro0
(0)

XBP1 CRISPR Activation Plasmid (h2)

sc-400131-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

XBP1 Lentiviral Activation Particles (h)

sc-400131-LAChGene ActivationPuro, Blast, Hygro0
(0)

XBP1 Lentiviral Activation Particles (h2)

sc-400131-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

XBP1 CRISPR Activation Plasmid (m)

sc-423727-ACTmGene ActivationPuro, Blast, Hygro0
(2)

XBP1 CRISPR Activation Plasmid (m2)

sc-423727-ACT-2mGene ActivationPuro, Blast, Hygro0
(2)

XBP1 Lentiviral Activation Particles (m)

sc-423727-LACmGene ActivationPuro, Blast, Hygro0
(2)

XBP1 Lentiviral Activation Particles (m2)

sc-423727-LAC-2mGene ActivationPuro, Blast, Hygro0
(2)

XBP siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

XBP1 siRNA (h)

sc-38627hGene SilencingN/A
35
(1)

XBP1 shRNA Plasmid (h)

sc-38627-SHhGene SilencingPuromycin
35
(1)

XBP1 shRNA (h) Lentiviral Particles

sc-38627-VhGene SilencingPuromycin
35
(1)

XBP1 siRNA (m)

sc-38628mGene SilencingN/A
9
(0)

XBP1 shRNA Plasmid (m)

sc-38628-SHmGene SilencingPuromycin
9
(0)

XBP1 shRNA (m) Lentiviral Particles

sc-38628-VmGene SilencingPuromycin
9
(0)