VSTM2B inhibitors are a class of chemical compounds designed to specifically target and inhibit the activity of the VSTM2B protein, a member of the V-set and transmembrane domain-containing family. VSTM2B is a protein involved in cell signaling and is believed to play a role in regulating cellular processes, potentially including immune responses and cell communication. Though the precise functions of VSTM2B are still under investigation, it is known to interact with other cell surface proteins, influencing pathways that are important for cellular homeostasis and signaling cascades. By inhibiting VSTM2B, these compounds block its ability to mediate interactions with other proteins or receptors, thereby interfering with the cellular processes in which it is involved.
The mechanism of action for VSTM2B inhibitors typically involves binding to functional regions of the VSTM2B protein, preventing it from engaging in its normal protein-protein interactions. This inhibition disrupts the signaling pathways associated with VSTM2B, potentially affecting downstream processes related to cellular communication and regulation. Researchers use VSTM2B inhibitors to study the biological role of this protein in various signaling pathways, aiming to understand how its inhibition alters cellular function and molecular networks. By targeting VSTM2B, these inhibitors provide valuable insights into the mechanisms that regulate cellular interactions and help to clarify the role of proteins like VSTM2B in maintaining cellular equilibrium, particularly in processes where precise protein signaling is essential for cellular coordination and response.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, known to affect various cellular processes including protein synthesis and autophagy. It might indirectly influence VSTM2B through these pathways. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $96.00 $250.00 $750.00 $1428.00 | 280 | |
A specific inhibitor of the vacuolar type H+-ATPase (V-ATPase), affecting autophagy and lysosomal acidification. It could indirectly affect VSTM2B-related functions. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Known to inhibit autophagy by preventing lysosome acidification. Given VSTM2B's potential involvement in related pathways, chloroquine may have an indirect effect. | ||||||
Autophagy Inhibitor, 3-MA | 5142-23-4 | sc-205596 sc-205596A | 50 mg 500 mg | $56.00 $256.00 | 113 | |
An inhibitor of autophagy by blocking class III PI3K. It might influence VSTM2B activity indirectly by modulating autophagic processes. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor, affecting various signaling pathways including autophagy. Its role in these pathways might indirectly impact VSTM2B. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Another PI3K inhibitor, known to affect autophagy and other cellular processes. It could have an indirect effect on VSTM2B. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An inhibitor of MEK, part of the MAPK/ERK pathway. It might influence VSTM2B indirectly through its role in signaling pathways. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
An inhibitor of p38 MAPK, which could indirectly affect VSTM2B through its influence on stress response and signaling pathways. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, impacting stress response and apoptosis pathways. Its indirect effect on VSTM2B could be through these pathways. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Known to influence various cellular processes including autophagy. It might have an indirect effect on VSTM2B-related functions. | ||||||