Chemical activators of Vmn1r86 can include a variety of aromatic compounds that engage the receptor in a specific manner leading to its activation. Alpha-ionone, for instance, mimics the natural scent molecules that ordinarily bind to Vmn1r86, initiating a conformational change within the protein structure that triggers the olfactory sensory neuron activation. Similarly, Beta-caryophyllene acts as an agonist for Vmn1r86 by directly associating with the receptor's ligand-binding domain, thereby initiating a G-protein signaling cascade that culminates in the perception of its odorant signal. Benzaldehyde and Ethyl vanillin operate through a similar mechanism, wherein their binding to Vmn1r86 leads to the activation of intracellular pathways involved in olfactory transduction.
Other chemicals such as Citral, Eugenol, Geraniol, and Limonene also activate Vmn1r86 by adhering to the active site of the receptor, which in turn triggers the G-protein coupled mechanisms intrinsic to the receptor's function, leading to the relay of olfactory information. Methyl anthranilate and Phenethyl alcohol further contribute to this array of activators by directly interacting with Vmn1r86, causing a structural change that initiates the signal transduction pathways. Vanillin and Veratraldehyde, too, activate Vmn1r86 by engaging the receptor through direct binding, which induces the signaling pathway and results in the activation of the olfactory sensory neurons responsible for the detection of their distinct scents. Each of these chemicals, by binding to Vmn1r86, effectively elicits the specific signal transduction pathways that facilitate the perception of their unique odors by the olfactory system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Ionone | 127-41-3 | sc-239157 | 100 g | $75.00 | ||
Activation of Vmn1r86 by alpha-ionone occurs as this chemical mimics the scent molecules that typically bind to and activate this olfactory receptor, causing a conformational change that triggers signal transduction pathways leading to olfactory sensory neuron activation. | ||||||
(−)-trans-Caryophyllene | 87-44-5 | sc-251281 sc-251281A sc-251281B sc-251281C | 1 ml 5 ml 25 ml 1 L | $81.00 $160.00 $446.00 $2918.00 | 1 | |
Beta-caryophyllene serves as an agonist for Vmn1r86, directly binding to the receptor's ligand-binding site, which activates the receptor and initiates a G-protein signaling cascade resulting in the perception of its specific odorant signal. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral activates Vmn1r86 by binding to the receptor's active site, causing an activation signal that leads to the olfactory response. This interaction specifically initiates signal transduction via G-protein coupled mechanisms inherent to this olfactory receptor's function. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
3-Ethoxy-4-hydroxybenzaldehyde can activate Vmn1r86 by binding to the receptor, which induces a conformational change and activates the G-protein coupled receptor pathway, leading to the transmission of olfactory information to the brain. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol activates Vmn1r86 by direct interaction with the receptor, engaging the olfactory G-protein coupled receptor pathways and resulting in the activation of the olfactory signal transduction that is characteristic of this receptor's response to specific odorant molecules. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol binds directly to Vmn1r86, activating the G-protein coupled receptor pathway and triggering a cascade of intracellular events that result in the detection of its floral scent by the olfactory system. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene activates Vmn1r86 through direct binding to the receptor, which induces activation of the G-protein signaling pathway and leads to the subsequent olfactory sensory neuron response. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol activates Vmn1r86 when it binds to the receptor's active site, causing a conformational change that initiates G-protein coupled signal transduction pathways, ultimately leading to the perception of its floral odor. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin activates Vmn1r86 through direct binding to the receptor, which induces the G-protein coupled receptor signaling pathway, resulting in the activation of the olfactory sensory neurons that detect vanillin's sweet and creamy scent. | ||||||