Date published: 2025-10-21

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U2AF65 Antibodies

Santa Cruz Biotechnology features a diverse variety of U2AF65 monoclonal antibodies for research focused on understanding U2AF65's role in pre-mRNA splicing and gene regulation. Multiple applications are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). U2AF65, a critical splicing factor, is involved in the recognition of the 3' splice site of pre-mRNA, playing a vital role in the maturation of mRNA and the regulation of gene expression. Its function is essential for proper cellular processes, and dysregulation of U2AF65 has been implicated in various diseases, including cancer. Understanding the dynamics of U2AF65 can provide insights into the mechanisms of splicing-related disorders and potential therapeutic targets. Researchers can explore U2AF65's interaction with other splicing factors and its role in alternative splicing events. Advanced visualization techniques using fluorescent conjugates such as horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC) enable detailed analysis of U2AF65 localization and function. Investigation of U2AF65's involvement in RNA processing pathways continues to reveal new aspects of gene regulation mechanisms. Santa Cruz Biotechnology monoclonal antibodies for U2AF65 support researchers worldwide in advancing scientific understanding of RNA splicing mechanisms and their impact on human health.

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U2AF65 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

U2AF65 Antibody (MC3)

sc-53942mouse IgG2b κ(h)WB, IP, IF, IHC(P)m, r, h
31
(13)

U2AF65 Antibody (C-8)

sc-166695mouse IgG1 κ1-300 (h)WB, IP, IF, ELISAm, r, h
3
(2)

U2AF65 Antibody (D-8)

sc-374333mouse IgM κ2-25 (h)WB, IP, IF, ELISAm, r, h

new

(3)

U2AF65 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

U2AF65 CRISPR/Cas9 KO Plasmid (h)

sc-402059hGene KnockoutGFP0
(0)

U2AF65 HDR Plasmid (h)

sc-402059-HDRhHomology Directed RepairPuromycin0
(0)

U2AF65 Double Nickase Plasmid (h)

sc-402059-NIChGene KnockoutPuromycin0
(0)

U2AF65 Double Nickase Plasmid (h2)

sc-402059-NIC-2hGene KnockoutPuromycin0
(0)

U2AF65 CRISPR/Cas9 KO Plasmid (m)

sc-423572mGene KnockoutGFP0
(0)

U2AF65 CRISPR/Cas9 KO Plasmid (m2)

sc-423572-KO-2m2Gene KnockoutGFP0
(0)

U2AF65 HDR Plasmid (m2)

sc-423572-HDR-2m2Homology Directed RepairPuromycin0
(0)

U2AF65 Double Nickase Plasmid (m)

sc-423572-NICmGene KnockoutPuromycin0
(0)

U2AF65 Double Nickase Plasmid (m2)

sc-423572-NIC-2mGene KnockoutPuromycin0
(0)

U2AF65 CRISPR Activation Products

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U2AF65 CRISPR Activation Plasmid (h)

sc-402059-ACThGene ActivationPuro, Blast, Hygro0
(0)

U2AF65 CRISPR Activation Plasmid (h2)

sc-402059-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

U2AF65 Lentiviral Activation Particles (h)

sc-402059-LAChGene ActivationPuro, Blast, Hygro0
(0)

U2AF65 Lentiviral Activation Particles (h2)

sc-402059-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

U2AF65 CRISPR Activation Plasmid (m)

sc-423572-ACTmGene ActivationPuro, Blast, Hygro0
(0)

U2AF65 CRISPR Activation Plasmid (m2)

sc-423572-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

U2AF65 Lentiviral Activation Particles (m)

sc-423572-LACmGene ActivationPuro, Blast, Hygro0
(0)

U2AF65 Lentiviral Activation Particles (m2)

sc-423572-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

U2AF65 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

U2AF65 siRNA (h)

sc-37667hGene SilencingN/A
1
(0)

U2AF65 shRNA Plasmid (h)

sc-37667-SHhGene SilencingPuromycin
1
(0)

U2AF65 shRNA (h) Lentiviral Particles

sc-37667-VhGene SilencingPuromycin
1
(0)

U2AF65 siRNA (m)

sc-37668mGene SilencingN/A0
(0)

U2AF65 shRNA Plasmid (m)

sc-37668-SHmGene SilencingPuromycin0
(0)

U2AF65 shRNA (m) Lentiviral Particles

sc-37668-VmGene SilencingPuromycin0
(0)