Date published: 2025-11-4

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Tyrosine Kinase Inhibitors

Santa Cruz Biotechnology now offers a broad range of Tyrosine Kinase Inhibitors for use in various applications. Tyrosine kinase inhibitors are crucial compounds in biochemical and molecular biology research, specifically designed to inhibit the activity of tyrosine kinases, enzymes responsible for the phosphorylation of tyrosine residues on proteins. These inhibitors are instrumental in studying signal transduction pathways, cellular communication, and the regulation of various cellular processes such as growth, differentiation, and metabolism. By selectively blocking tyrosine kinases, researchers can dissect the roles of specific signaling pathways and understand how aberrations in these pathways contribute to diseases such as cancer and autoimmune disorders. In the scientific community, tyrosine kinase inhibitors are utilized to explore the intricate networks of cellular signaling, identify potential biomarkers, and develop novel experimental models. Their application extends to examining the effects of genetic mutations on kinase activity, explaining mechanisms of drug resistance, and validating targets for new scientific approaches. The availability of high-purity tyrosine kinase inhibitors from Santa Cruz Biotechnology ensures that experiments are conducted with precision and reproducibility, providing reliable data essential for advancing scientific knowledge. By offering a comprehensive selection of these inhibitors, Santa Cruz Biotechnology supports researchers in their quest to uncover the complexities of cellular signaling and develop innovative strategies for addressing biological challenges. View detailed information on our available Tyrosine Kinase Inhibitors by clicking on the product name.

Items 121 to 123 of 123 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Adaphostin

241127-58-2sc-291833
sc-291833A
10 mg
50 mg
$129.00
$560.00
(0)

Adaphostin acts as a tyrosine kinase inhibitor, characterized by its ability to disrupt ATP binding through unique steric hindrance. This compound selectively targets specific kinase domains, leading to altered phosphorylation states of key substrates. Its structural conformation allows for precise interactions with the active site, influencing downstream signaling cascades. Additionally, Adaphostin's electronic characteristics may enhance its binding affinity, contributing to its distinct kinetic profile in kinase modulation.

Imatinib-d8

1092942-82-9sc-488072
sc-488072A
1 mg
10 mg
$556.00
$4085.00
(0)

Imatinib-d8 functions as a selective tyrosine kinase inhibitor, exhibiting unique isotopic labeling that enhances its tracking in biochemical assays. Its deuterated structure influences reaction kinetics, potentially altering metabolic stability and interaction dynamics. The compound's specific binding affinity to the ATP site is modulated by its conformational flexibility, allowing for tailored interactions with various kinase isoforms. This specificity can lead to distinct downstream signaling alterations, providing insights into kinase regulation.

3-Amino-5-nitrobenzoic acid

618-84-8sc-276008
sc-276008A
1 g
5 g
$64.00
$180.00
(0)

3-Amino-5-nitrobenzoic acid exhibits unique properties as a tyrosine kinase modulator, where its nitro group significantly alters the electronic environment, enhancing binding affinity to target proteins. The compound's structural features facilitate specific hydrogen bonding interactions, which can stabilize enzyme-substrate complexes. This stabilization may influence the phosphorylation process, affecting downstream signaling pathways and cellular responses, thereby showcasing its role in biochemical interactions.