TRAM1L1 Activators
TRAM1L1 activators comprise a specialized chemical class recognized for their capacity to modulate the activity of TRAM1L1, a protein encoded by the TRAM1L1 gene. TRAM1L1, also known as Translocation-associated membrane protein 1-like protein 1, is a relatively understudied protein with limited known functions. However, emerging evidence suggests its potential involvement in various cellular processes, including protein trafficking, membrane translocation, and organelle biogenesis. Activators targeting TRAM1L1 likely exert their effects by influencing its activity, stability, or subcellular localization. These activators play a vital role in deciphering the biological functions of TRAM1L1 and its contributions to cellular physiology.
Structurally, TRAM1L1 activators may exhibit a diverse array of chemical scaffolds, reflecting the complexity required for effective engagement with the target protein. These molecules may contain specific binding motifs or functional groups facilitating their interaction with TRAM1L1, thereby modulating its activity with precision. Understanding the structural and biochemical properties of TRAM1L1 activators is crucial for unraveling the molecular mechanisms underlying the functions of this protein and its involvement in cellular processes. Further exploration of the pharmacological characteristics and biological significance of TRAM1L1 activators holds promise for advancing our understanding of cellular physiology and may offer insights into novel strategies for manipulating cellular functions in various biological contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
May upregulate TRAM1L1 as part of the unfolded protein response (UPR) by inducing ER stress. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Could increase TRAM1L1 expression by causing ER calcium depletion, another trigger for the UPR. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Might enhance TRAM1L1 expression by disrupting ER-Golgi transport, inducing ER stress. | ||||||
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $67.00 $156.00 | 16 | |
Could induce TRAM1L1 expression by inhibiting HSP90, leading to protein misfolding and ER stress. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Might increase TRAM1L1 expression by inhibiting the proteasome, causing protein accumulation and ER stress. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
As a hormone, might modulate TRAM1L1 expression through estrogen receptor pathways, potentially influencing ER function. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Could modulate TRAM1L1 expression as part of its broad effects on cellular stress responses and signaling pathways. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
May influence TRAM1L1 expression through its anti-inflammatory effects, potentially affecting ER stress pathways. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
As a histone deacetylase inhibitor, might enhance TRAM1L1 expression by altering chromatin structure and accessibility. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Could affect TRAM1L1 expression through its role in cellular differentiation and development, potentially involving ER stress pathways. | ||||||