TP1 Activators
The TP1 Activators are a group of compounds that can influence the functional activity of TP1, which is a component of the telomerase complex. Some compounds such as Epigallocatechin Gallate (EGCG), GRN163L (Imetelstat), BIBR1532, MST-312, Rh2, and Costunolide are known to inhibit telomerase activity, which could be achieved through direct interactions with the telomerase complex, including TP1. These compounds might act by binding to the telomerase complex or altering the epigenetic state of the telomerase genes, leading to impaired function of TP1.
In contrast, other compounds such as TAT-2C, Astragaloside IV, Oleuropein, and Cycloastragenol are known to enhance telomerase activity, through interactions with the telomerase complex, including TP1. These compounds might act by stabilizing the telomerase complex or directly stimulating its activity, leading to enhanced function of TP1.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a polyphenol in green tea, has been shown to inhibit telomerase activity, potentially through a direct interaction with the telomerase complex, which includes TP1. | ||||||
Astragaloside IV | 84687-43-4 | sc-257103 | 20 mg | $57.00 | 1 | |
Astragaloside IV, a saponin found in Astragalus, can stimulate telomerase activity, potentially through an interaction with the telomerase complex, including TP1. | ||||||
Oleuropein | 32619-42-4 | sc-286622 sc-286622A sc-286622B sc-286622C | 500 mg 1 g 10 g 100 g | $359.00 $530.00 $791.00 $6773.00 | 2 | |
Oleuropein, a compound found in olive leaf extract, has been found to stimulate telomerase activity, possibly through an interaction with the telomerase complex, including TP1. | ||||||
20(S)- Ginsenoside Rh2 | 78214-33-2 | sc-394416 sc-394416A | 1 mg 10 mg | $90.00 $265.00 | ||
Rh2, a ginsenoside, has been found to inhibit telomerase activity, potentially through an interaction with the telomerase complex, including TP1. | ||||||
Costunolide | 553-21-9 | sc-203555 sc-203555A | 1 mg 10 mg | $83.00 $171.00 | 1 | |
Costunolide, a sesquiterpene lactone, has been found to inhibit telomerase activity, potentially through an interaction with the telomerase complex, including TP1. | ||||||