The chemical class of TMEM202 Activators encompasses a diverse group of compounds that can modulate the function of the transmembrane protein TMEM202 through various modes of action on cellular signaling pathways. These activators are not unified by a common chemical structure or specific mechanism of action but are rather characterized by their ability to influence the cellular environment in which TMEM202 operates. The activation process typically involves altering the concentration of intracellular messengers, modifying enzymatic activity that affects protein function, or changing the phosphorylation state of proteins within the cell.
By influencing key regulatory systems within the cell, these activators can lead to changes in the activity of TMEM202. For instance, they can affect the levels of secondary messengers such as cyclic AMP (cAMP) or calcium ions, which are crucial for the regulation of numerous cellular processes. Moreover, these molecules can alter the activity of kinases and phosphatases, which in turn can change the phosphorylation status of TMEM202, possibly leading to an alteration in its activity. Additionally, by modulating the activity of proteins involved in signal transduction pathways, these activators can have downstream effects on the functional state of TMEM202, such as changing its conformation, localization, or interaction with other cellular components.These compounds are typically used in research to dissect the biological pathways that TMEM202 is part of and understand its role within the cell. The ability to modulate the activity of TMEM202 through these chemicals provides a valuable tool for exploring the fundamental aspects of cell biology. The precise effects of these activators on TMEM202, and the subsequent cellular responses, provide insights into the protein's function and its contribution to the complex network of intracellular signals. Through detailed biochemical and cell-based assays, researchers can map out the influence these activators have on TMEM202 and use this information to build a more comprehensive understanding of cellular physiology.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which could possibly activate TMEM202 by modulating various transmembrane signaling processes. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), involved in signaling cascades that could possibly activate TMEM202 by affecting transmembrane protein function. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Ionomycin is a calcium ionophore, raising intracellular calcium levels, which could possibly activate TMEM202 by influencing transmembrane protein signaling. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein inhibits tyrosine kinases, which could possibly activate TMEM202 by altering phosphorylation states and signaling. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a MEK inhibitor that could possibly activate TMEM202 by affecting the MAPK/ERK pathway, influencing transmembrane protein activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor, which could possibly activate TMEM202 by altering AKT signaling pathways, impacting transmembrane proteins. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor, which could possibly activate TMEM202 by modulating signaling pathways related to transmembrane proteins. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
Gö 6983 is a pan-PKC inhibitor, which could possibly activate TMEM202 by modulating signaling pathways involving PKC that transmembrane proteins may be part of. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $449.00 | 61 | |
BAPTA-AM is an intracellular calcium chelator, which could possibly activate TMEM202 by affecting calcium-mediated transmembrane signaling. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $27.00 $52.00 | 37 | |
2-APB affects store-operated calcium entry, which could possibly activate TMEM202 by modulating transmembrane protein function. |