TMEM191B Inhibitors

Transmembrane protein 191B (TMEM191B) is a member of the transmembrane protein family, a diverse group of proteins characterized by their ability to span the lipid bilayer of cellular membranes. Though specific functional details of TMEM191B are still emerging, proteins in this family typically play critical roles in a variety of cellular processes, including signaling, transport, and cellular architecture.

TMEM191B is encoded by the TMEM191B gene located on chromosome 4 and is expressed in several tissues throughout the body. As a transmembrane protein, TMEM191B is likely to be involved in the maintenance of membrane integrity, contributing to the structure and function of the organelles or the cell itself. Its topology, which includes both extracellular and cytoplasmic domains, suggests it might participate in signaling cascades by acting as a receptor or a molecular scaffold that organizes other signaling proteins in close proximity.The protein's structure, with multiple transmembrane domains, implies that it could function in the transport of molecules across the membrane. This could involve the selective passage of ions or small molecules, contributing to cellular homeostasis and the regulation of the intracellular environment.