Date published: 2026-4-5

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TLR4 Antibodies

Santa Cruz Biotechnology provides a broad selection of TLR4 monoclonal antibodies for research focused on understanding Toll-like receptor 4 in immune response. TLR4 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). TLR4 is a critical component of the innate immune system, recognizing pathogen-associated molecular patterns and initiating inflammatory responses. The activation of TLR4 plays a vital role in the detection of bacterial lipopolysaccharides, making it essential for host defense against infections. TLR4 is implicated in various diseases, including sepsis and autoimmune disorders, highlighting its importance in both health and disease. Researchers studying TLR4 can explore its role in cellular signaling pathways and inflammatory responses. Understanding TLR4 function contributes to the development of new therapeutic strategies for immune-related conditions. Investigating TLR4 expression patterns helps reveal its distribution across different tissue types and cell populations. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance their understanding of immune system regulation and disease mechanisms.

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TLR4 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

TLR4 Antibody (25)

sc-293072mouse IgG1 κ198-395 (m)WB, IP, IF, IHC(P)m, r, h and canine
698
(107)

TLR4 Antibody (HTA125)

sc-13593mouse IgG2a κ(h)IP, IF, IHC(P), FCMh
80
(11)

TLR4 Antibody (MTS510)

sc-13591rat IgG2a(m)IP, IF, FCMm, r, h
53
(7)

TLR4 Antibody (76B357.1)

sc-52962mouse IgG2b(h)WB, IP, FCMm, r, h
23
(7)

TLR4 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TLR4 CRISPR/Cas9 KO Plasmid (h2)

sc-400068-KO-2hGene KnockoutGFP
2
(0)

TLR4 Double Nickase Plasmid (h)

sc-400068-NIChGene KnockoutPuromycin
2
(0)

TLR4 Double Nickase Plasmid (h2)

sc-400068-NIC-2hGene KnockoutPuromycin
2
(0)

TLR4 CRISPR/Cas9 KO Plasmid (m)

sc-423419mGene KnockoutGFP
3
(0)

TLR4 HDR Plasmid (m)

sc-423419-HDRmHomology Directed RepairPuromycin
3
(0)

TLR4 Double Nickase Plasmid (m)

sc-423419-NICmGene KnockoutPuromycin
3
(0)

TLR4 CRISPR/Cas9 KO Plasmid (bovine)

sc-437333bovine0
(0)

TLR4 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TLR4 CRISPR Activation Plasmid (h)

sc-400068-ACThGene ActivationPuro, Blast, Hygro
2
(0)

TLR4 CRISPR Activation Plasmid (h2)

sc-400068-ACT-2hGene ActivationPuro, Blast, Hygro
2
(0)

TLR4 Lentiviral Activation Particles (h)

sc-400068-LAChGene ActivationPuro, Blast, Hygro
2
(0)

TLR4 CRISPR Activation Plasmid (m)

sc-423419-ACTmGene ActivationPuro, Blast, Hygro
3
(0)

TLR4 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TLR4 siRNA (h)

sc-40260hGene SilencingN/A
76
(0)

TLR4 shRNA Plasmid (h)

sc-40260-SHhGene SilencingPuromycin
76
(0)

TLR4 shRNA (h) Lentiviral Particles

sc-40260-VhGene SilencingPuromycin
76
(0)

TLR4 siRNA (m)

sc-40261mGene SilencingN/A
59
(2)

TLR4 shRNA Plasmid (m)

sc-40261-SHmGene SilencingPuromycin
59
(2)

TLR4 shRNA (m) Lentiviral Particles

sc-40261-VmGene SilencingPuromycin
59
(2)

TLR4 siRNA (r)

sc-156001rGene SilencingN/A
16
(0)

TLR4 shRNA Plasmid (r)

sc-156001-SHrGene SilencingPuromycin
16
(0)

TLR4 shRNA (r) Lentiviral Particles

sc-156001-VrGene SilencingPuromycin
16
(0)