TAF II p30 Inhibitors
TAF II p30 inhibitors represent a class of chemical compounds that specifically target the TAF II p30 protein, a critical component of the TFIID complex involved in transcriptional regulation. The TFIID complex plays a pivotal role in the initiation of transcription, a fundamental process in gene expression. TAF II p30, as a subunit of TFIID, contributes to the assembly of the pre-initiation complex at the promoter region of genes, facilitating the recruitment of RNA polymerase II and other transcription factors.
TAF II p30 inhibitors is designed to interact selectively with the TAF II p30 protein, disrupting its normal function in transcriptional initiation. By binding to TAF II p30, these inhibitors can modulate the assembly of the pre-initiation complex, thereby influencing the overall transcriptional activity of specific genes. The development of TAF II p30 inhibitors represents a targeted approach to manipulate gene expression at the transcriptional level, allowing researchers to gain insights into the underlying molecular mechanisms of gene regulation. The study and utilization of these inhibitors contribute to advancing our understanding of the intricate processes involved in transcription, offering potential applications in basic research and molecular biology studies.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can modulate the activity of various transcription factors and might alter the function of TAF II p30 by changing the transcriptional machinery's dynamics. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol acts as a modulator for multiple signaling pathways and could influence the activity of proteins that interact with TAF II p30, altering its function. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane is known to affect the expression of certain genes and thus can influence the activity of transcription factors indirectly. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, by modulating kinase pathways, can change transcription factor activity and therefore might affect TAF II p30 indirectly. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin can influence gene expression and potentially affect transcription factor activities by altering signaling pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is an inhibitor of MEK, which could indirectly affect transcription factor function by altering ERK/MAPK signaling. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 inhibits PI3K, potentially affecting transcription factor activity downstream of PI3K/AKT signaling. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 inhibits p38 MAPK, potentially affecting transcription factor activity by modulation of this signaling pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor, which can indirectly affect the activities of transcription factors through AP-1. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a PI3K inhibitor like LY294002 and can lead to changes in transcription factor activity by affecting signaling pathways. | ||||||