This class of chemicals, termed Supervillin Activators, comprises various compounds that indirectly influence the functional dynamics of Supervillin in cell motility and cytoskeletal organization. These chemicals modulate different cellular signaling pathways and processes, thereby creating an environment conducive to Supervillin's activity within the cell. Phosphatidylinositol 3,4,5-Trisphosphate, Forskolin, and Adenosine 3',5'-cyclic monophosphate (cAMP) are examples that affect secondary messenger systems. By influencing these messengers, they modulate the signaling pathways that govern cytoskeletal dynamics, potentially enhancing Supervillin's role in cell motility. Calcium Chloride, providing calcium ions, plays a pivotal role in various cellular processes, including those influencing cytoskeleton and cell motility, thereby indirectly impacting Supervillin's activity.
Other compounds like Phorbol 12-Myristate 13-Acetate (PMA) and Y-27632 target specific pathways like protein kinase C and the RhoA/ROCK pathway, respectively. These pathways are directly involved in cytoskeletal rearrangements, thus indirectly modulating Supervillin's role in these processes. Growth factors like Epidermal Growth Factor and signaling molecules such as 1-Azakenpaullone (a Wnt pathway agonist) directly influence cell motility and cytoskeletal organization. Their effects on these processes can create an indirect impact on the functional dynamics of Supervillin.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $66.00 $262.00 | 1 | |
As a source of calcium ions, it influences cellular processes including cytoskeletal dynamics, affecting Supervillin's activity. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
cAMP, a secondary messenger, modulates signaling pathways relevant to Supervillin's function in cell motility. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Increases cAMP levels, influencing signaling pathways and processes relevant to Supervillin's function. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C (PKC), influencing cytoskeletal organization and potentially Supervillin's activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences Wnt/β-catenin signaling, involved in cytoskeletal organization, potentially affecting Supervillin activity. | ||||||
Sodium nitroprusside dihydrate | 13755-38-9 | sc-203395 sc-203395A sc-203395B | 1 g 5 g 100 g | $43.00 $85.00 $158.00 | 7 | |
As a nitric oxide donor, modulates cytoskeletal dynamics, influencing Supervillin activity in cell motility. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor influencing cell motility and cytoskeletal organization, potentially affecting Supervillin's role. | ||||||
Lovastatin | 75330-75-5 | sc-200850 sc-200850A sc-200850B | 5 mg 25 mg 100 mg | $29.00 $90.00 $339.00 | 12 | |
Influences cell signaling pathways related to cytoskeletal dynamics and cell motility, potentially affecting Supervillin. | ||||||