SUHW3 Activators
SUHW3 Activators' mechanisms of action involve a diverse array of biochemical pathways, each contributing to the regulation and enhancement of its activity within the cellular milieu. For instance, certain activators work by modulating intracellular second messenger systems, like cAMP and calcium ions. The elevation of cAMP through adenylate cyclase stimulation leads to subsequent activation of protein kinase A, which can phosphorylate transcription factors. These phosphorylated transcription factors may then interact with SUHW3, augmenting its activity. Similarly, the rise in intracellular calcium levels through the action of calcium ionophores triggers calcium-dependent signaling cascades. This can lead to the activation of calcium-dependent protein kinases, which may influence the network of proteins that regulate SUHW3, thereby indirectly increasing its functional capacity within the cell.
Moreover, other activators exert their effects by targeting specific enzymes or signaling molecules, thereby modulating the cellular context in which SUHW3 operates. Inhibition of protein phosphatases leads to a sustained phosphorylation state of proteins, keeping transcription factors active and potentially enhancing the regulatory role of SUHW3. Bioactive lipids and unsaturated fatty acids can activate distinct receptors or alter membrane dynamics, which in turn can influence downstream signaling pathways that affect SUHW3 activity. Additionally, the manipulation of intracellular zinc levels can directly impact zinc finger-containing transcription factors, including SUHW3, by changing their binding affinity and transcriptional activity. Lastly, the inhibition of key kinases involved in multifaceted signaling pathways, such as GSK-3, can result in alterations to transcriptional regulation, indirectly leading to the activation of SUHW3.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylyl cyclase, increasing cAMP levels in cells. Elevated cAMP enhances protein kinase A (PKA) activity, which can phosphorylate transcription factors that may interact with SUHW3, leading to its functional activation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Diacylglycerol (DAG) analog that activates protein kinase C (PKC). PKC phosphorylation can affect transcription factors and cofactors that modulate SUHW3 activity. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
A calcium ionophore that increases intracellular calcium concentration, activating calcium-dependent signaling pathways, which could affect the function of SUHW3 by altering the cellular context in which it operates. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $27.00 $37.00 | 5 | |
A beta-adrenergic agonist that increases cAMP levels, thereby activating PKA. PKA can then influence the transcriptional activity of factors that associate with SUHW3, modulating its activity. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
A cell-permeable cAMP analog that activates PKA. PKA may phosphorylate proteins that regulate the activity of SUHW3, enhancing its function. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A calcium ionophore that raises intracellular calcium levels, triggering calcium-dependent protein kinases that could promote the activation of SUHW3 through downstream signaling events. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $285.00 $520.00 $1300.00 | 78 | |
A potent inhibitor of protein phosphatases 1 and 2A, maintaining the phosphorylation state of proteins, which could keep transcription factors in an active state that promotes the functional activity of SUHW3. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
A bioactive lipid that activates sphingosine-1-phosphate receptors, leading to downstream effects on transcriptional regulation that could enhance the activity of SUHW3. | ||||||
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $36.00 $102.00 $569.00 $1173.00 | 10 | |
Unsaturated fatty acid that can modulate membrane fluidity and potentially affect signal transduction pathways involving membrane-bound proteins or receptors that influence SUHW3 activation. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Increases intracellular zinc levels, which can influence zinc finger-containing transcription factors and their co-factors, potentially enhancing the transcriptional regulatory activity of SUHW3. | ||||||