Molecular structure of Oleic Acid, CAS Number: 112-80-1
Oleic Acid (CAS 112-80-1)
See product citations (10)
Alternate Names:
cis-9-Octadecenoic acid;Elainic acid
Application:
Oleic Acid is an anti-proliferative agent and activator of PKC and CaMKII
CAS Number:
112-80-1
Purity:
≥99%
Molecular Weight:
282.46
Molecular Formula:
C18H34O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Oleic Acid, a monounsaturated fatty acid originally derived from Olea europaea, may act to be an anti-proliferative agent. This compound has also been reported to promote neuronal differentiation in murine cell cultures. Mechanistic studies suggest that these Oleic Acid effects are mediated by PPARbeta. Furthermore, Oleic Acid has demonstrated the ability to stimulate an increase in secretion of collagen I, TGF-beta secretion, and extracellular signal-regulated kinase1/2. Oleic Acid is an activator of PKC and CaMKII.
Oleic Acid (CAS 112-80-1) References
- Astrocyte-synthesized oleic acid behaves as a neurotrophic factor for neurons. | Medina, JM. and Tabernero, A. 2002. J Physiol Paris. 96: 265-71. PMID: 12445905
- PPARbeta agonists trigger neuronal differentiation in the human neuroblastoma cell line SH-SY5Y. | Di Loreto, S., et al. 2007. J Cell Physiol. 211: 837-47. PMID: 17390299
- Oleic acid promotes changes in the subcellular distribution of protein kinase C in isolated hepatocytes. | Díaz-Guerra, MJ., et al. 1991. J Biol Chem. 266: 23568-76. PMID: 1748635
- Active components and clinical applications of olive oil. | Waterman, E. and Lockwood, B. 2007. Altern Med Rev. 12: 331-42. PMID: 18069902
- Oleate induces a myofibroblast-like phenotype in mesangial cells. | Mishra, R. and Simonson, MS. 2008. Arterioscler Thromb Vasc Biol. 28: 541-7. PMID: 18096831
- Anti-cancer targeting telomerase inhibitors: β-rubromycin and oleic acid. | Mizushina, Y., et al. 2012. Mini Rev Med Chem. 12: 1135-43. PMID: 22876944
- Antitumor effect of oleic acid; mechanisms of action: a review. | Carrillo, C., et al. 2012. Nutr Hosp. 27: 1860-5. PMID: 23588432
- Oleic acid phase behavior from molecular dynamics simulations. | Janke, JJ., et al. 2014. Langmuir. 30: 10661-7. PMID: 25133680
- Oleic acid exhibits an expressive anti-inflammatory effect in croton oil-induced irritant contact dermatitis without the occurrence of toxicological effects in mice. | Pegoraro, NS., et al. 2021. J Ethnopharmacol. 267: 113486. PMID: 33091495
- Free fatty acid treatment of mouse preimplantation embryos demonstrates contrasting effects of palmitic acid and oleic acid on autophagy. | Leung, ZCL., et al. 2022. Am J Physiol Cell Physiol. 322: C833-C848. PMID: 35319901
- Oleic acid-related anti-inflammatory effects in force-stressed PdL fibroblasts are mediated by H3 lysine acetylation associated with altered IL10 expression. | Schuldt, L., et al. 2022. Epigenetics. 17: 1892-1904. PMID: 35763686
- Oleic Acid Protects Endothelial Cells from Silica-Coated Superparamagnetic Iron Oxide Nanoparticles (SPIONs)-Induced Oxidative Stress and Cell Death. | Repar, N., et al. 2022. Int J Mol Sci. 23: PMID: 35806014
- Oroxin A ameliorates the oleic acid-induced A549 cell injury through the suppression of pyroptosis and degradation of alveolar surfactant. | Huang, J., et al. 2022. An Acad Bras Cienc. 94: e20211400. PMID: 36477822
- Update on Anti-Inflammatory Molecular Mechanisms Induced by Oleic Acid. | Santa-María, C., et al. 2023. Nutrients. 15: PMID: 36615882
Inhibitor of:
apoL7b, C7orf47, C8orf37, ChREBP, DGK-δ, FA2H, HSDL2, Lipocalin-15, Lipocalin-9, N-myristoyltransferase 1, Peroxin 11α, Pex13p, Pex14p, PM20D1, PP2A-Cα, SCP-2, UNC119B, and ZNF729.Activator of:
β-1,4-Gal-T2, δ-FR, 0610037D15Rik, 17β-HSD11, 1700013G24Rik, 1810030N24Rik, 2310004I24Rik, 2310033E01Rik, 2410131K14Rik, 2900097C17Rik, 4833423E24Rik, 9130011J15Rik, 9130014G24Rik, A-FABP, ACAA2, ACAD-12, ACAT-2, ACBD4, ACBD5, ACOX2, ACSBG1, ACSL4, ACSL5, ACSVL1, ACSVL6, ADRP, AI747699, AMPKβ1, Angptl4, apoAL, apoE, apoM, ARH1, ARRDC5, ARV1, ATGL, AUP1, Aytl1b, BSA, C/EBP ε, C/EBP ζ, C11orf74, C12orf41, C12orf43, C12orf49, C12orf52, C12orf54, C12orf59_D630042F21Rik, C20orf77, C5orf33, C5orf36, C6orf167, CAGE, Calcitriol, CaMKII, Candida albicans, CCDC127, CCDC147, CCT8L1, CDS1, CEACAM19, Ces1c, CIDE-B, CIDE-C, Citrate Lyase, CLPTM1, CMV gB, connexin 31.1, COX1, cPKC βI, CRBP II, CREBRF, cryptdin 4, CYP27C1, CYP4A1, CYP4F22, CYP4V3, Cytokeratin 23, Cytokeratin 9, D8S2298E, Dbil5, DDHD2, DECR2, DGAT1, DGAT2, DGAT2L6, DGK-α, DGK-θ, DHRS1, DNA pol ε, Edc4, EG624219, eIF4E, ELOVL5, ELOVL6, Embigin, ENHO, epsin2, Ethanolamine kinase 2, EVPLL, FABP12, FACL5, FACL6, FADS1, FAM115C, FAM23A, FAR1, FBF1, FIT2, Flavivirus, G2A, GAP-43, Gastric Lipase, GDPD4, GLTPD1, Glutamine-rich 2, Glycophorin A, GNPAT, GOLGA6L10, GPAM, GPAT2, GPD1L, GPR120, GPR40, GPR84, group IID sPLA2, group IVC sPLA2, group IVD sPLA2, group V PLA2, GUP1, HAO2, HAO3, HemT-1, Hep C NS4a, Hep C NS5a, HNF-4γ, HNF-4B, hornerin, HRASLS3, I-FABP, ICE-LAP6, IGLON5, Keratin 73, KRTAP1-4, KRTAP19, KRTAP19-3, KRTAP5-4, KRTAP9-1, KRTAP9-2, KRTAP9-L1, L-FABP, L-Glycerol-3-Phosphate Oxidase, Lamin B receptor, LCE1B, LCE1C, LCE1E, Lce1g, Lce1m, LCE2A, LCE2D, LCE3B, LCE3D, LCE4A, LCE5A, LELP1, leptin, Lipin-2, LIPK, Lipocalin-6, LL-37, LOC100041019, LOC727909, LPAAT-β, LPAAT-ε, LPAAT-ζ, LPCAT1, LPCAT2, LRAT, LRRC49, LYG2, LYPLA1, LYPLA3, LYPLAL1, LYRM2, LYRM5, MafA, MATH-5, MBOAT2, MBOAT5, MCT13, Measles H, MIPP, Monoglyceride Lipase, MOSPD2, MOSPD3, motilin, Mucin 4, Myl12a, Mylc2b, n-Dodecylmaltoside, NAPE-PLD, NAT-8L, NBPF6, NCB5OR, NPP6, NrCAM, NUDT12, Olfr323, Olfr325, OR13A1, OR2A42, OR2T27, OR4C12, OR4K15, OR4L1, OR51AA4, OR5D13, ORP-7_Osbpl7, ORP-8, p49/STRAP, PAcP, PAFAH1B3, Pancreatic Lipase, PAP-2b, PC-PLD3, PC-PLD5, PCMTD1, PCYT2, PDP2, Perilipin, Peroxin 11γ, Peroxin 19, Peroxin 2, Peroxin 6, Pex13p, Pex14p, Pex7p, PHLPPL, PI 3-kinase p101, PI 4-kinase α, PI 4-kinase II α, PIG-preY, PIG-V, PIP2, PIS1, PKC, Pkc1, PKN, PLA2G4B, Plb1, Plb3, PLC β4, PLD, PLRP1, PLRP2, PLSCR3, PLSCR5, Pma2, PNPLA1, PNPLA7, PON1, PP2A-Aβ, PP2A-Cα, PPAR alpha, PPT2, PRSS51, Pseudo, Psg22, PSS2, PTPDC1, PTPLB, pUb-R, RDH11, RDH12, RDH14, RDHE2, resistin, RNF208, RNPC3, RORα, Rotavirus, RPE, RPL12, Rpp14, SAA1, saposin, SCAP, SCD, SCD1, SCD2, SCD3, SCD4, SCD5, SCG10, Sciellin, SCP2, SEC14L2, sEH, Seipin, SERINC1, SERINC4, SKI-1, SMAP1L, SMS2, SOAT1, SOAT2, SPANX-E, SPCS2, SPP, SPRR2A, SPRR2D, SPRR4, SR-B1, SREBP-1, SSAT2, StARD10, StARD13, StARD7, SUHW3, suprabasin, Synaptotagmin VIII, Syntaxin 18, TGase1, THEM5, TIGD6, TMEM195, TMEM41B, TMSL3, Trav12d-3, Trav12n-2, Trav13d-4, Trav14n-1, Trav16d, Trav4d-3, Trav4n-4, Trav6d-3, TREK-1, TRIM73, TRIM74, Trk B, TSP50, TSSK 5, TTC39B, TTLL6, TTP-α, TUSC5, UCP2, UGCG, UGT8, VDR, VPS13C, VSIG6, WBP2, WBSCR22, Ypk1, ZADH1, ZDHHC11B, ZDHHC14, ZDHHC15, ZDHHC25, ZDHHC8, Zfp808, and ZSCAN5B.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Oleic Acid, 1 g | sc-200797C | 1 g | $37.00 | |||
Oleic Acid, 10 g | sc-200797 | 10 g | $104.00 | |||
Oleic Acid, 100 g | sc-200797A | 100 g | $580.00 | |||
Oleic Acid, 250 g | sc-200797B | 250 g | $1196.00 |