| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rottlerin | 82-08-6 | sc-3550 sc-3550B sc-3550A sc-3550C sc-3550D sc-3550E | 10 mg 25 mg 50 mg 1 g 5 g 20 g | $84.00 $166.00 $302.00 $2091.00 $5212.00 $16657.00 | 51 | |
Rottlerin is a selective inhibitor of SRPK1, known for its unique ability to disrupt the phosphorylation of serine/arginine-rich proteins. It interacts with the active site of SRPK1, altering the enzyme's conformation and inhibiting its kinase activity. This modulation affects splicing factor activity and downstream signaling pathways. Rottlerin's distinct binding affinity and kinetic profile highlight its role in regulating cellular processes, particularly in the context of RNA metabolism and protein synthesis. | ||||||
SRPIN 340 | 218156-96-8 | sc-394310 | 10 mg | $226.00 | 1 | |
SRPIN 340 is a selective inhibitor of SRPK1 that uniquely alters the phosphorylation dynamics of serine/arginine-rich proteins. It engages with the enzyme's active site, inducing conformational changes that hinder its kinase function. This interaction not only impacts the phosphorylation cascade but also influences the stability and localization of splicing factors. The compound's specific binding characteristics and kinetic behavior underscore its role in modulating cellular signaling networks and RNA processing mechanisms. | ||||||