Date published: 2026-3-9

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SPOP Antibodies

Santa Cruz Biotechnology features a diverse variety of SPOP Antibodies for advanced research in molecular biology. SPOP Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). SPOP, or Speckle-type POZ protein, plays a critical role in regulating protein degradation and is involved in various cellular processes, including transcriptional regulation and signal transduction. The significance of SPOP is highlighted by its association with several cancers, making it a key target for therapeutic research. Understanding SPOP function can provide insights into tumorigenesis and potential treatment strategies. Research has shown that SPOP mutations are particularly prevalent in prostate cancer, making it an important area of investigation. Studying SPOP expression patterns and interactions can reveal new pathways in cancer development. The relationship between SPOP and other cellular proteins continues to be an active area of research, offering promising directions for future studies. Santa Cruz Biotechnology monoclonal antibodies for SPOP research support scientists worldwide in advancing our understanding of cancer biology and developing new therapeutic approaches.

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SPOP Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SPOP Antibody (B-8)

sc-377206mouse IgG2b κ351-374 (h)WB, IP, IF, ELISAm, r, h
6
(9)

SPOP CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPOP CRISPR/Cas9 KO Plasmid (h2)

sc-401290-KO-2hGene KnockoutGFP0
(0)

SPOP HDR Plasmid (h2)

sc-401290-HDR-2hHomology Directed RepairPuromycin0
(0)

SPOP CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPOP CRISPR Activation Plasmid (h)

sc-401290-ACThGene ActivationPuro, Blast, Hygro0
(0)

SPOP CRISPR Activation Plasmid (h2)

sc-401290-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SPOP Lentiviral Activation Particles (h)

sc-401290-LAChGene ActivationPuro, Blast, Hygro0
(0)

SPOP siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPOP siRNA (h)

sc-63056hGene SilencingN/A
2
(0)

SPOP shRNA Plasmid (h)

sc-63056-SHhGene SilencingPuromycin
2
(0)

SPOP shRNA (h) Lentiviral Particles

sc-63056-VhGene SilencingPuromycin
2
(0)

SPOP siRNA (m)

sc-63057mGene SilencingN/A0
(0)

SPOP shRNA Plasmid (m)

sc-63057-SHmGene SilencingPuromycin0
(0)

SPOP shRNA (m) Lentiviral Particles

sc-63057-VmGene SilencingPuromycin0
(0)