Date published: 2025-9-11

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Sphingolipids

Santa Cruz Biotechnology now offers a broad range of sphingolipids for use in various applications. Sphingolipids are a class of complex lipids containing a sphingoid base backbone, which are essential components of cell membranes and play crucial roles in cellular signaling and structural integrity. These compounds are significant in scientific research due to their involvement in numerous biological processes and their impact on cell function and health. In biochemistry and cell biology, sphingolipids are studied to understand their role in membrane structure, signaling pathways, and their influence on cell behavior, including apoptosis, proliferation, and differentiation. Researchers utilize sphingolipids to investigate mechanisms of diseases associated with lipid metabolism disorders and to explore potential targets for novel strategies, although not in a clinical context. In neuroscience, sphingolipids are crucial for studying the function and organization of the nervous system, given their role in myelin sheath formation and neuron function. Environmental scientists study sphingolipids to understand their role in cellular responses to environmental stressors and their potential as biomarkers for environmental monitoring. Additionally, sphingolipids are employed in the development of advanced materials and nanotechnology, where their unique structural properties can be harnessed for creating biomimetic materials and drug delivery systems. Analytical chemists use sphingolipids in techniques such as mass spectrometry and chromatography to analyze lipid compositions and understand lipidomics, the large-scale study of pathways and networks of cellular lipids in biological systems. The broad applications of sphingolipids in scientific research underscore their importance in advancing our knowledge of fundamental biological processes and driving innovations across multiple disciplines. View detailed information on our available sphingolipids by clicking on the product name.

Items 41 to 50 of 64 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

D-erythro-Ceramide C8 1-phosphate

sc-300407
1 mg
$202.00
(0)

D-erythro-Ceramide C8 1-phosphate is a sphingolipid that plays a crucial role in cellular signaling and membrane dynamics. Its phosphate group enhances hydrophilicity, promoting interactions with membrane proteins and influencing lipid bilayer properties. This compound is involved in key signaling pathways, modulating cellular responses to stress and inflammation. Its unique structure allows for specific interactions with receptors, impacting cellular communication and function.

D-erythro-Ceramine C8

sc-300408
1 mg
$79.00
(0)

D-erythro-Ceramine C8 is a sphingolipid characterized by its long hydrophobic tail, which facilitates its integration into lipid bilayers, thereby influencing membrane fluidity and stability. This compound exhibits unique molecular interactions, particularly with cholesterol, enhancing membrane organization. Its structural features allow it to participate in lipid raft formation, crucial for cellular signaling and protein localization, thereby affecting various cellular processes and dynamics.

D-erythro-Dihydrosphingosine 1-phosphate

sc-300409
1 mg
$166.00
(0)

D-erythro-Dihydrosphingosine 1-phosphate is a bioactive sphingolipid that plays a pivotal role in cellular signaling pathways. Its unique phosphate group enhances hydrophilicity, promoting interactions with membrane proteins and influencing intracellular signaling cascades. This compound is involved in regulating cell growth, survival, and migration through its engagement with specific receptors, thereby modulating various physiological responses and cellular behaviors.

N-Stearoyldihydro-D-erythro-Sphingosine

2304-80-5sc-205937
5 mg
$637.00
(0)

N-Stearoyldihydro-D-erythro-Sphingosine is a complex sphingolipid characterized by its long-chain fatty acid moiety, which contributes to its hydrophobic properties and membrane integration. This compound participates in lipid bilayer formation, influencing membrane fluidity and stability. Its unique structure allows for specific interactions with lipid rafts, facilitating the clustering of signaling molecules and impacting cellular communication and membrane dynamics.

L-erythro-Sphingosine (synthetic)

6036-75-5sc-202687
5 mg
$6400.00
(0)

L-erythro-Sphingosine is a synthetic sphingolipid distinguished by its dual hydrocarbon chains, which enhance its amphipathic nature. This compound plays a crucial role in modulating membrane microdomains, affecting lipid organization and protein localization. Its ability to form hydrogen bonds with polar head groups facilitates unique interactions within lipid bilayers, influencing cellular signaling pathways and membrane permeability. Additionally, it exhibits distinct reaction kinetics in enzymatic pathways, impacting sphingolipid metabolism.

3-Ketosphingosine trifluoroacetate salt

19767-16-9sc-223547
1 mg
$200.00
(0)

3-Ketosphingosine trifluoroacetate salt is a sphingolipid derivative characterized by its unique trifluoroacetate moiety, which enhances its solubility and reactivity. This compound participates in lipid metabolism, influencing the synthesis and degradation of sphingolipids. Its structural features allow for specific interactions with enzymes, potentially altering reaction rates and pathways. The presence of the trifluoroacetate group may also affect its interactions with cellular membranes, impacting lipid bilayer dynamics and stability.

D-erythro-Sphingosine sulfate salt

56607-20-6sc-203017
25 mg
$400.00
(0)

D-erythro-Sphingosine sulfate salt is a sphingolipid derivative distinguished by its sulfate group, which imparts unique hydrophilic properties. This compound plays a crucial role in cellular signaling and membrane dynamics, facilitating interactions with specific receptors and proteins. Its sulfate moiety can influence the formation of lipid rafts, thereby modulating membrane fluidity and organization. Additionally, it may participate in various metabolic pathways, affecting cellular homeostasis and lipid turnover.

N-Heptadecanoyl-D-erythro-sphingosine

67492-16-4sc-394348
5 mg
$340.00
(0)

N-Heptadecanoyl-D-erythro-sphingosine is a long-chain sphingolipid characterized by its fatty acyl chain, which enhances its hydrophobic interactions within lipid bilayers. This compound is integral to membrane structure, influencing lipid packing and stability. Its unique acyl chain length can affect the fluidity and permeability of membranes, while also participating in the formation of specialized lipid domains. Furthermore, it may engage in specific protein interactions, impacting cellular signaling pathways and metabolic processes.

N-Lignoceroyl-DL-dihydrosphingosine

75196-33-7sc-215462
sc-215462A
1 mg
5 mg
$210.00
$420.00
(0)

N-Lignoceroyl-DL-dihydrosphingosine is a complex sphingolipid distinguished by its unique dihydro structure, which alters its interaction with membrane components. This compound exhibits distinct hydrophobic properties, promoting the formation of lipid rafts that facilitate protein clustering and signaling. Its long-chain fatty acyl moiety contributes to membrane rigidity, influencing cellular communication and transport mechanisms. Additionally, it may play a role in modulating enzymatic activities within lipid metabolism.

L-erythro MAPP

143492-38-0 (D-isomer)sc-205740
sc-205740A
5 mg
25 mg
$59.00
$182.00
(0)

L-erythro MAPP is a distinctive sphingolipid that exhibits unique structural properties, including a branched hydrocarbon chain that enhances its interaction with lipid membranes. This compound plays a crucial role in modulating membrane curvature and stability, influencing the organization of lipid rafts. Its specific stereochemistry allows for selective binding to certain proteins, potentially altering signal transduction pathways and cellular responses. The compound's hydrophobic regions contribute to its integration within lipid bilayers, affecting membrane dynamics.