Date published: 2025-12-16

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SPEN CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. SPEN gene silencers are available as SPEN CRISPR/Cas9 Knockout plasmids and SPEN Double Nickase Plasmids. SPEN CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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SPEN CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPEN CRISPR/Cas9 KO Plasmid (h)

sc-406083hGene KnockoutGFP0
(0)

SPEN HDR Plasmid (h)

sc-406083-HDRhHomology Directed RepairPuromycin0
(0)

SPEN Double Nickase Plasmid (h)

sc-406083-NIChGene KnockoutPuromycin0
(0)

SPEN Double Nickase Plasmid (h2)

sc-406083-NIC-2hGene KnockoutPuromycin0
(0)

SPEN CRISPR/Cas9 KO Plasmid (m)

sc-425128mGene KnockoutGFP0
(0)

SPEN HDR Plasmid (m)

sc-425128-HDRmHomology Directed RepairPuromycin0
(0)

SPEN Double Nickase Plasmid (m)

sc-425128-NICmGene KnockoutPuromycin0
(0)

SPEN Double Nickase Plasmid (m2)

sc-425128-NIC-2mGene KnockoutPuromycin0
(0)

SPEN CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPEN CRISPR Activation Plasmid (h)

sc-406083-ACThGene ActivationPuro, Blast, Hygro0
(0)

SPEN CRISPR Activation Plasmid (h2)

sc-406083-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SPEN Lentiviral Activation Particles (h)

sc-406083-LAChGene ActivationPuro, Blast, Hygro0
(0)

SPEN Lentiviral Activation Particles (h2)

sc-406083-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SPEN CRISPR Activation Plasmid (m)

sc-425128-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SPEN CRISPR Activation Plasmid (m2)

sc-425128-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SPEN Lentiviral Activation Particles (m)

sc-425128-LACmGene ActivationPuro, Blast, Hygro0
(0)

SPEN Lentiviral Activation Particles (m2)

sc-425128-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)