SPACA7 Activators
Sperm acrosome-associated 7 (SPACA7) is a protein that, as its name suggests, is associated with the acrosome of sperm cells. The acrosome is a cap-like structure over the anterior half of the sperm's head and is found in the Golgi apparatus during spermatogenesis. It contains enzymes that are critical for fertilization because they help the sperm penetrate the outer layers of the egg.Proteins associated with the acrosome, like SPACA7, often play roles in the acrosome reaction, a crucial event in fertilization where the contents of the acrosome are released to facilitate the sperm's passage through the zona pellucida, the glycoprotein layer surrounding the oocyte. SPACA7 is thought to be one of the proteins involved in this process, although its exact biochemical function and mechanism of action are less well characterized than some other acrosomal proteins.
The importance of acrosomal proteins is underscored by their potential link to male fertility. Abnormalities or deficiencies in these proteins can lead to failed or inefficient acrosome reactions, which can be a cause of infertility.Molecular studies of SPACA7 may include its expression patterns, post-translational modifications, interaction with other acrosomal proteins, and its role in sperm maturation and the acrosome reaction. Given the complexity of fertilization and the number of proteins involved, SPACA7 is likely a piece of a larger puzzle that ensures the success of this critical biological process.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which can indirectly influence SPACA7 activity by modulating signaling pathways involved in sperm maturation and function. | ||||||
8-Bromoadenosine 3′,5′-cyclic monophosphate | 23583-48-4 | sc-217493B sc-217493 sc-217493A sc-217493C sc-217493D | 25 mg 50 mg 100 mg 250 mg 500 mg | $108.00 $169.00 $295.00 $561.00 $835.00 | 2 | |
A cAMP analog that bypasses the receptor-mediated activation, potentially altering the signaling pathways that could modulate SPACA7 activity in sperm cells. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
A non-specific inhibitor of phosphodiesterases, increasing cAMP levels, thereby possibly affecting SPACA7 activity through altered signaling. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol found in green tea, known for its antioxidant properties, which might influence SPACA7 by altering the oxidative state in sperm, indirectly affecting its activity. | ||||||
L-Carnitine | 541-15-1 | sc-205727 sc-205727A sc-205727B sc-205727C | 1 g 5 g 100 g 250 g | $23.00 $34.00 $79.00 $179.00 | 3 | |
An amino acid derivative that is known to improve sperm motility, potentially affecting SPACA7 activity indirectly through enhanced cellular metabolism. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc plays a crucial role in sperm development and function, potentially influencing SPACA7 activity. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $73.00 | 2 | |
Involved in nucleic acid synthesis and repair, its presence is crucial for sperm health and might indirectly influence SPACA7 activity. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $71.00 $184.00 | 1 | |
An antioxidant that improves sperm quality, potentially affecting SPACA7 activity indirectly through enhanced mitochondrial function. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $62.00 | 1 | |
A trace element important for sperm motility, which might indirectly influence SPACA7 activity through its role in antioxidant defense mechanisms. | ||||||