Date published: 2026-1-9

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SPACA CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. SPACA gene silencers are available as SPACA CRISPR/Cas9 Knockout plasmids and SPACA Double Nickase Plasmids. SPACA CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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SPACA CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPACA1 CRISPR/Cas9 KO Plasmid (h)

sc-406974hGene KnockoutGFP0
(0)

SPACA1 Double Nickase Plasmid (h)

sc-406974-NIChGene KnockoutPuromycin0
(0)

SPACA1 Double Nickase Plasmid (h2)

sc-406974-NIC-2hGene KnockoutPuromycin0
(0)

SPACA1 CRISPR/Cas9 KO Plasmid (m)

sc-426667mGene KnockoutGFP0
(0)

SPACA1 HDR Plasmid (m)

sc-426667-HDRmHomology Directed RepairPuromycin0
(0)

SPACA1 Double Nickase Plasmid (m)

sc-426667-NICmGene KnockoutPuromycin0
(0)

SPACA1 Double Nickase Plasmid (m2)

sc-426667-NIC-2mGene KnockoutPuromycin0
(0)

SPACA3 CRISPR/Cas9 KO Plasmid (h)

sc-407167hGene KnockoutGFP0
(0)

SPACA3 HDR Plasmid (h)

sc-407167-HDRhHomology Directed RepairPuromycin0
(0)

SPACA3 Double Nickase Plasmid (h)

sc-407167-NIChGene KnockoutPuromycin0
(0)

SPACA3 Double Nickase Plasmid (h2)

sc-407167-NIC-2hGene KnockoutPuromycin0
(0)

SPACA3 CRISPR/Cas9 KO Plasmid (m)

sc-429149mGene KnockoutGFP0
(0)

SPACA3 HDR Plasmid (m)

sc-429149-HDRmHomology Directed RepairPuromycin0
(0)

SPACA3 Double Nickase Plasmid (m)

sc-429149-NICmGene KnockoutPuromycin0
(0)

SPACA3 Double Nickase Plasmid (m2)

sc-429149-NIC-2mGene KnockoutPuromycin0
(0)

SPACA4 CRISPR/Cas9 KO Plasmid (h)

sc-417661hGene KnockoutGFP0
(0)

SPACA4 HDR Plasmid (h)

sc-417661-HDRhHomology Directed RepairPuromycin0
(0)

SPACA4 Double Nickase Plasmid (h)

sc-417661-NIChGene KnockoutPuromycin0
(0)

SPACA4 Double Nickase Plasmid (h2)

sc-417661-NIC-2hGene KnockoutPuromycin0
(0)

SPACA4 CRISPR/Cas9 KO Plasmid (m)

sc-427391mGene KnockoutGFP0
(0)

SPACA4 HDR Plasmid (m)

sc-427391-HDRmHomology Directed RepairPuromycin0
(0)

SPACA4 Double Nickase Plasmid (m)

sc-427391-NICmGene KnockoutPuromycin0
(0)

SPACA4 Double Nickase Plasmid (m2)

sc-427391-NIC-2mGene KnockoutPuromycin0
(0)

SPACA5 CRISPR/Cas9 KO Plasmid (h)

sc-417020hGene KnockoutGFP0
(0)

SPACA5 HDR Plasmid (h)

sc-417020-HDRhHomology Directed RepairPuromycin0
(0)

SPACA5 Double Nickase Plasmid (h)

sc-417020-NIChGene KnockoutPuromycin0
(0)

SPACA5 Double Nickase Plasmid (h)

sc-417310-NIChGene KnockoutPuromycin0
(0)

SPACA5 Double Nickase Plasmid (h2)

sc-417020-NIC-2hGene KnockoutPuromycin0
(0)

SPACA5 CRISPR/Cas9 KO Plasmid (m)

sc-435516mGene KnockoutGFP0
(0)

SPACA5 HDR Plasmid (m)

sc-435516-HDRmHomology Directed RepairPuromycin0
(0)

SPACA5 Double Nickase Plasmid (m)

sc-435516-NICmGene KnockoutPuromycin0
(0)

SPACA5 Double Nickase Plasmid (m2)

sc-435516-NIC-2mGene KnockoutPuromycin0
(0)

SPACA5B CRISPR/Cas9 KO Plasmid (h)

sc-417310hGene KnockoutGFP0
(0)

SPACA5B HDR Plasmid (h)

sc-417310-HDRhHomology Directed RepairPuromycin0
(0)

SPACA5B Double Nickase Plasmid (h2)

sc-417310-NIC-2hGene KnockoutPuromycin0
(0)

SPACA7 CRISPR/Cas9 KO Plasmid (h)

sc-409022hGene KnockoutGFP0
(0)

SPACA7 HDR Plasmid (h)

sc-409022-HDRhHomology Directed RepairPuromycin0
(0)

SPACA7 Double Nickase Plasmid (h)

sc-409022-NIChGene KnockoutPuromycin0
(0)

SPACA7 Double Nickase Plasmid (h2)

sc-409022-NIC-2hGene KnockoutPuromycin0
(0)

SPACA7 CRISPR/Cas9 KO Plasmid (m)

sc-429688mGene KnockoutGFP0
(0)

SPACA7 HDR Plasmid (m)

sc-429688-HDRmHomology Directed RepairPuromycin0
(0)

SPACA7 Double Nickase Plasmid (m)

sc-429688-NICmGene KnockoutPuromycin0
(0)

SPACA7 Double Nickase Plasmid (m2)

sc-429688-NIC-2mGene KnockoutPuromycin0
(0)

SPACA CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPACA1 CRISPR Activation Plasmid (h)

sc-406974-ACThGene ActivationPuro, Blast, Hygro0
(0)

SPACA1 CRISPR Activation Plasmid (h2)

sc-406974-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SPACA1 Lentiviral Activation Particles (h)

sc-406974-LAChGene ActivationPuro, Blast, Hygro0
(0)

SPACA1 Lentiviral Activation Particles (h2)

sc-406974-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SPACA1 CRISPR Activation Plasmid (m)

sc-426667-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SPACA1 CRISPR Activation Plasmid (m2)

sc-426667-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SPACA1 Lentiviral Activation Particles (m)

sc-426667-LACmGene ActivationPuro, Blast, Hygro0
(0)

SPACA1 Lentiviral Activation Particles (m2)

sc-426667-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SPACA3 CRISPR Activation Plasmid (h)

sc-407167-ACThGene ActivationPuro, Blast, Hygro0
(0)

SPACA3 CRISPR Activation Plasmid (h2)

sc-407167-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SPACA3 Lentiviral Activation Particles (h)

sc-407167-LAChGene ActivationPuro, Blast, Hygro0
(0)

SPACA3 Lentiviral Activation Particles (h2)

sc-407167-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SPACA3 CRISPR Activation Plasmid (m)

sc-429149-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SPACA3 CRISPR Activation Plasmid (m2)

sc-429149-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SPACA3 Lentiviral Activation Particles (m)

sc-429149-LACmGene ActivationPuro, Blast, Hygro0
(0)

SPACA3 Lentiviral Activation Particles (m2)

sc-429149-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SPACA4 CRISPR Activation Plasmid (h)

sc-417661-ACThGene ActivationPuro, Blast, Hygro0
(0)

SPACA4 CRISPR Activation Plasmid (h2)

sc-417661-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SPACA4 Lentiviral Activation Particles (h)

sc-417661-LAChGene ActivationPuro, Blast, Hygro0
(0)

SPACA4 Lentiviral Activation Particles (h2)

sc-417661-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SPACA4 CRISPR Activation Plasmid (m)

sc-427391-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SPACA4 CRISPR Activation Plasmid (m2)

sc-427391-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SPACA4 Lentiviral Activation Particles (m)

sc-427391-LACmGene ActivationPuro, Blast, Hygro0
(0)

SPACA4 Lentiviral Activation Particles (m2)

sc-427391-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SPACA5 CRISPR Activation Plasmid (h)

sc-417020-ACThGene ActivationPuro, Blast, Hygro0
(0)

SPACA5 CRISPR Activation Plasmid (h)

sc-417310-ACThGene ActivationPuro, Blast, Hygro0
(0)

SPACA5 CRISPR Activation Plasmid (h2)

sc-417020-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SPACA5 Lentiviral Activation Particles (h)

sc-417020-LAChGene ActivationPuro, Blast, Hygro0
(0)

SPACA5 Lentiviral Activation Particles (h)

sc-417310-LAChGene ActivationPuro, Blast, Hygro0
(0)

SPACA5 Lentiviral Activation Particles (h2)

sc-417020-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SPACA5 CRISPR Activation Plasmid (m)

sc-435516-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SPACA5 CRISPR Activation Plasmid (m2)

sc-435516-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SPACA5 Lentiviral Activation Particles (m)

sc-435516-LACmGene ActivationPuro, Blast, Hygro0
(0)

SPACA5 Lentiviral Activation Particles (m2)

sc-435516-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SPACA5B CRISPR Activation Plasmid (h2)

sc-417310-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SPACA5B Lentiviral Activation Particles (h2)

sc-417310-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SPACA7 CRISPR Activation Plasmid (h)

sc-409022-ACThGene ActivationPuro, Blast, Hygro0
(0)

SPACA7 CRISPR Activation Plasmid (h2)

sc-409022-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SPACA7 Lentiviral Activation Particles (h)

sc-409022-LAChGene ActivationPuro, Blast, Hygro0
(0)

SPACA7 Lentiviral Activation Particles (h2)

sc-409022-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SPACA7 CRISPR Activation Plasmid (m)

sc-429688-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SPACA7 CRISPR Activation Plasmid (m2)

sc-429688-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SPACA7 Lentiviral Activation Particles (m)

sc-429688-LACmGene ActivationPuro, Blast, Hygro0
(0)

SPACA7 Lentiviral Activation Particles (m2)

sc-429688-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)