SNX17 Activators
The chemical class SNX17 Activators includes compounds that indirectly influence the activity of SNX17 by modulating endosomal trafficking and sorting processes. These compounds primarily act on various aspects of cellular trafficking, such as endocytosis, acidification of endosomes, and cytoskeletal dynamics, which are crucial for the proper functioning of SNX17 in sorting membrane proteins.
For example, compounds like Dynasore and Monensin impact the dynamics of endocytosis and endosomal pH, respectively. By altering these processes, they can create conditions that affect the sorting and trafficking functions of SNX17. Similarly, inhibitors of clathrin-mediated endocytosis, such as Pitstop 2 and Chlorpromazine, can influence the pathways where SNX17 operates, thereby potentially modifying its activity. Additionally, compounds affecting cytoskeletal elements (like Nocodazole and Cytochalasin D) and cellular signaling pathways (such as Wortmannin and Genistein) can indirectly influence SNX17's role in endosomal sorting. These effects are a result of the interconnected nature of cellular trafficking pathways, where changes in one aspect can ripple through and impact various processes, including those mediated by SNX17.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Dynasore inhibits dynamin, impacting endocytosis and potentially altering the endosomal sorting process where SNX17 is involved. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
Monensin disrupts endosomal pH and trafficking, which could indirectly influence SNX17's role in sorting. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $98.00 $255.00 $765.00 $1457.00 | 280 | |
Bafilomycin A1 inhibits vacuolar-type H+-ATPase, affecting endosomal acidification and potentially impacting SNX17-mediated sorting. | ||||||
Pitstop 2 | 1419320-73-2 | sc-507418 | 10 mg | $360.00 | ||
Pitstop 2 inhibits clathrin-mediated endocytosis, potentially influencing the trafficking pathways where SNX17 operates. | ||||||
5-(N-Ethyl-N-isopropyl)-Amiloride | 1154-25-2 | sc-202458 | 5 mg | $104.00 | 20 | |
EIPA blocks macropinocytosis, potentially influencing endosomal trafficking and indirectly affecting SNX17. | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $61.00 $110.00 | 21 | |
Chlorpromazine disrupts clathrin-mediated endocytosis, which might indirectly impact SNX17 activity in endosomal sorting. | ||||||
Filipin III | 480-49-9 | sc-205323 sc-205323A | 500 µg 1 mg | $118.00 $148.00 | 26 | |
Filipin III disrupts cholesterol-rich membrane domains, potentially affecting membrane trafficking and SNX17's sorting function. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubules, impacting intracellular trafficking and potentially influencing SNX17-mediated sorting. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Cytochalasin D inhibits actin polymerization, affecting cytoskeletal dynamics and potentially SNX17's role in endosomal sorting. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin inhibits PI3 kinase, impacting endocytic trafficking, which could indirectly affect SNX17 activity. | ||||||