Date published: 2025-10-7

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Smo Antibodies

Santa Cruz Biotechnology features a diverse variety of Smo Antibodies for advanced research in cell signaling and development. Smo Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Smoothened (Smo) functions as a key component of the Hedgehog signaling pathway, regulating cell growth, differentiation, and tissue patterning during embryonic development. Smo expression patterns can be effectively analyzed using specific detection methods across various experimental applications. Understanding Smo activity provides valuable insights into cellular development and tissue organization. Abnormal Smo function has been linked to various cancers and developmental disorders, highlighting its significance in disease research. Investigating Smo mechanisms helps identify new therapeutic approaches for treating related pathologies. Santa Cruz Biotechnology monoclonal antibodies for Smo research enable scientists to make meaningful contributions to understanding disease mechanisms and developing targeted treatments.

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Smo Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SMO/Smoothened Antibody (E-5)

sc-166685mouse IgG2a κ488-787 (h)WB, IP, IF, ELISAm, r, h
95
(13)

Smo CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SMO/Smoothened CRISPR/Cas9 KO Plasmid (h)

sc-400491hGene KnockoutGFP
1
(0)

SMO/Smoothened HDR Plasmid (h)

sc-400491-HDRhHomology Directed RepairPuromycin
1
(0)

SMO/Smoothened Double Nickase Plasmid (h)

sc-400491-NIChGene KnockoutPuromycin
1
(0)

SMO/Smoothened Double Nickase Plasmid (h2)

sc-400491-NIC-2hGene KnockoutPuromycin
1
(0)

SMO/Smoothened CRISPR/Cas9 KO Plasmid (m)

sc-435662mGene KnockoutGFP0
(0)

SMO/Smoothened HDR Plasmid (m)

sc-435662-HDRmHomology Directed RepairPuromycin0
(0)

SMO/Smoothened Double Nickase Plasmid (m)

sc-435662-NICmGene KnockoutPuromycin0
(0)

SMO/Smoothened Double Nickase Plasmid (m2)

sc-435662-NIC-2mGene KnockoutPuromycin0
(0)

Smo CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SMO/Smoothened CRISPR Activation Plasmid (h)

sc-400491-ACThGene ActivationPuro, Blast, Hygro
1
(0)

SMO/Smoothened CRISPR Activation Plasmid (h2)

sc-400491-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

SMO/Smoothened Lentiviral Activation Particles (h)

sc-400491-LAChGene ActivationPuro, Blast, Hygro
1
(0)

SMO/Smoothened Lentiviral Activation Particles (h2)

sc-400491-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

SMO/Smoothened CRISPR Activation Plasmid (m)

sc-435662-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SMO/Smoothened CRISPR Activation Plasmid (m2)

sc-435662-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SMO/Smoothened Lentiviral Activation Particles (m)

sc-435662-LACmGene ActivationPuro, Blast, Hygro0
(0)

SMO/Smoothened Lentiviral Activation Particles (m2)

sc-435662-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Smo siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SMO/Smoothened siRNA (h)

sc-40161hGene SilencingN/A
8
(0)

SMO/Smoothened shRNA Plasmid (h)

sc-40161-SHhGene SilencingPuromycin
8
(0)

SMO/Smoothened shRNA (h) Lentiviral Particles

sc-40161-VhGene SilencingPuromycin
8
(0)

SMO/Smoothened siRNA (m)

sc-40162mGene SilencingN/A0
(0)

SMO/Smoothened shRNA Plasmid (m)

sc-40162-SHmGene SilencingPuromycin0
(0)

SMO/Smoothened shRNA (m) Lentiviral Particles

sc-40162-VmGene SilencingPuromycin0
(0)