SKIV2L2 Activators
SKIV2L2 Activators are distinct chemical entities designed to intensify the functional performance of SKIV2L2, a protein critical to RNA surveillance and degradation. These activators function through several direct and indirect pathways. Direct enhancement of SKIV2L2's functionality occurs through the provision of ATP, an essential energy molecule for the RNA helicase activity of SKIV2L2. Uridine, a component of RNA, can also indirectly enhance SKIV2L2's functionality by increasing the pool of RNA that SKIV2L2 processes.
Indirect activators like Caffeine, AICAR, Resveratrol, Metformin, Salicylic Acid, Lithium Chloride, Rapamycin, N-acetylcysteine, Deferoxamine, and Oxaloacetate operate through altering various cellular processes such as metabolism and stress responses. These alterations place demand on RNA surveillance and degradation mechanisms, subsequently enhancing the functionality of SKIV2L2. These compounds underscore the intricate interplay between SKIV2L2 and the cellular environment, demonstrating how changes in metabolic and stress responses can effectively lead to enhanced SKIV2L2 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine 5′-Triphosphate, disodium salt | 987-65-5 | sc-202040 sc-202040A | 1 g 5 g | $38.00 $74.00 | 9 | |
ATP is the primary energy currency in the cell, providing energy for numerous cellular functions. SKIV2L2, being an RNA helicase, requires ATP for its function. Hence, ATP availability directly enhances the functional activity of SKIV2L2. | ||||||
Uridine | 58-96-8 | sc-296685 sc-296685A | 1 g 25 g | $60.00 $98.00 | 1 | |
Uridine is a nucleoside which can indirectly impact SKIV2L2 activity by increasing the RNA pool which this protein processes. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine is known to affect various cellular processes including RNA metabolism. It can indirectly enhance SKIV2L2 functionality by increasing the demand for RNA surveillance and degradation. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR is an AMPK activator. AMPK activation leads to metabolic stress that can increase the demand for RNA surveillance and degradation, theoretically enhancing the activity of SKIV2L2. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a natural phenol, can influence cellular metabolism and stress responses, which may indirectly increase the need for RNA surveillance and degradation, enhancing SKIV2L2 activity. | ||||||
Metformin-d6, Hydrochloride | 1185166-01-1 | sc-218701 sc-218701A sc-218701B | 1 mg 5 mg 10 mg | $286.00 $806.00 $1510.00 | 1 | |
Metformin, a common drug for type 2 diabetes, influences cellular metabolism and can increase the demand for RNA surveillance and degradation, indirectly enhancing SKIV2L2 functionality. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $46.00 $92.00 $117.00 | 3 | |
Salicylic acid can induce cellular stress responses, which may increase the demand for RNA surveillance and degradation, indirectly enhancing SKIV2L2 activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride can influence various signaling pathways and cellular stress responses, potentially increasing the demand for RNA surveillance and degradation, and hence enhancing SKIV2L2 activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor. Inhibition of mTOR can lead to increased autophagy and cellular stress responses, which increases the demand for RNA surveillance and degradation, indirectly enhancing SKIV2L2 functionality. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
N-acetylcysteine is a precursor to glutathione and can influence cellular stress responses, potentially increasing the demand for RNA surveillance and degradation, enhancing SKIV2L2 activity. | ||||||