SKI-1 Activators

The chemical class of SKI-1 Activators encompasses a variety of compounds that can potentially stimulate or modulate the activity of SKI-1, a protease involved in the regulation of lipid metabolism and stress response. This class includes several statins, like Lovastatin, Simvastatin, Rosuvastatin, and Atorvastatin, which can influence cholesterol biosynthesis pathways, potentially leading to the indirect activation of SKI-1 through the processing of SREBPs.

Additionally, compounds like Mevalonic Acid and 25-Hydroxycholesterol, involved in cholesterol metabolism, can impact the regulation of SKI-1. PPAR agonists, such as Pioglitazone and Fenofibrate, and AMPK activators like Metformin, AICAR, and Berberine, are included due to their role in modulating lipid metabolism, potentially affecting SKI-1. Oleic Acid, as a fatty acid, could also influence lipid metabolic pathways, potentially impacting SKI-1 activity.