SH3TC1 Inhibitors
SH3TC1 Inhibitors refer to a diverse group of chemicals chosen based on SH3TC1's potential involvement in protein-protein interactions via its SH3 domains. Such domains are pivotal for several cellular operations like endocytosis, cell signaling, and cytoskeleton modulation. Src Inhibitor 1 and PP1, for instance, target Src family kinases, often associated with SH3 domains. Zoledronic acid, on the other hand, offers insights into any possible role of SH3TC1 in osteoclast function, given that some SH3 domain proteins are involved in bone dynamics.
The emphasis on cytoskeleton dynamics is clear with the inclusion of compounds like Cytochalasin D, Latrunculin A, and Swinholide A. If SH3TC1 plays any part in shaping the cellular structure or movement, these agents provide a window into such functions. Furthermore, by incorporating inhibitors like Dynasore and CK-666, we tap into SH3TC1's possible involvement in endocytic processes and actin branching.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Src kinase inhibitor I | 179248-59-0 | sc-204303 sc-204303A | 1 mg 10 mg | $52.00 $200.00 | 11 | |
SH3 domains can be found in Src family kinases. By inhibiting Src kinases, this compound may influence SH3TC1 if it interacts with these kinases. | ||||||
Zoledronic acid, anhydrous | 118072-93-8 | sc-364663 sc-364663A | 25 mg 100 mg | $90.00 $251.00 | 5 | |
Some SH3 domain-containing proteins are involved in osteoclast maturation. Zoledronic acid affects osteoclast function and might indirectly influence SH3TC1. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $87.00 | 44 | |
As some SH3 domains are implicated in endocytosis, Dynasore, an inhibitor of dynamin, might indirectly modulate SH3TC1's role in endocytosis. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
This compound disrupts actin filaments. If SH3TC1 is involved in cytoskeleton dynamics, this can influence its interactions. | ||||||
Neomycin sulfate | 1405-10-3 | sc-3573 sc-3573A | 1 g 5 g | $26.00 $34.00 | 20 | |
It's known to block phospholipase C-mediated processes, and if SH3TC1 is involved in this signaling, its activity can be affected. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
A broad tyrosine kinase inhibitor. Given that many SH3 domain proteins interact with tyrosine kinases, Genistein can influence SH3TC1's interactions. | ||||||
PP1 Analog II, 1NM-PP1 | 221244-14-0 | sc-203214 sc-203214A | 1 mg 5 mg | $106.00 $520.00 | 10 | |
A Src family kinase inhibitor. If SH3TC1 interacts with Src family kinases, its activity might be modified by PP1. | ||||||
Swinholide A, Theonella swinhoei | 95927-67-6 | sc-205914 | 10 µg | $135.00 | ||
Another actin-disrupting agent. It provides an avenue to explore SH3TC1's potential involvement in cytoskeletal processes. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $134.00 $502.00 | 7 | |
Cdc42 inhibitor. Given the broad roles of small GTPases and their interactions with SH3 domain proteins, ML141 might influence SH3TC1. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $315.00 $1020.00 | 5 | |
Arp2/3 complex inhibitor. As Arp2/3 complex is crucial for actin branching and some SH3 domain proteins play roles in this, CK-666 can potentially impact SH3TC1. | ||||||