Ser/Thr Protein Kinase Inhibitors
Items 281 to 284 of 284 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
8-Hydroxyadenosine-3′,5′-monophosphorothioate, Rp-isomer | sc-391035 | 1 µmol | $327.00 | |||
8-Hydroxyadenosine-3′,5′-monophosphorothioate, Rp-isomer, acts as a potent modulator of Ser/Thr protein kinases through its unique phosphorothioate backbone, which enhances binding affinity and stability in enzymatic interactions. This compound exhibits distinct conformational flexibility, allowing it to engage with specific kinase active sites effectively. Its ability to mimic natural substrates influences phosphorylation dynamics, altering signaling pathways and cellular responses. The compound's stereochemistry plays a crucial role in dictating its interaction profiles, impacting kinase selectivity and regulatory mechanisms. | ||||||
Dabrafenib-D9 | 1423119-98-5 | sc-397070 | 1 mg | $618.00 | ||
Dabrafenib-D9 is a selective inhibitor of Ser/Thr protein kinases, characterized by its unique isotopic labeling that enhances its tracking in biochemical assays. This compound exhibits a high affinity for specific kinase domains, facilitating precise molecular interactions that modulate phosphorylation events. Its distinct kinetic profile allows for nuanced regulation of signaling cascades, influencing downstream cellular processes. The compound's structural features contribute to its ability to disrupt typical kinase activity, providing insights into regulatory mechanisms. | ||||||
Ro-31-8220 in solution | 138489-18-6 | sc-358721 | 1 mg | $104.00 | 2 | |
Ro-31-8220 is a potent inhibitor of Ser/Thr protein kinases, distinguished by its ability to selectively target and bind to the ATP-binding site of these enzymes. This compound exhibits unique interaction dynamics, stabilizing the inactive conformation of kinases and effectively blocking substrate phosphorylation. Its rapid kinetics enable fine-tuning of signaling pathways, while its structural characteristics promote specificity, allowing for detailed exploration of kinase regulation in cellular contexts. | ||||||
AZD2014 | 1009298-59-2 | sc-364420 | 5 mg | $303.00 | 2 | |
AZD2014 is a selective inhibitor of Ser/Thr protein kinases, characterized by its unique binding affinity for the ATP-binding pocket. This compound disrupts kinase activity by inducing conformational changes that prevent substrate access. Its distinct reaction kinetics facilitate the modulation of signaling cascades, while its structural features enhance selectivity among various kinases, providing insights into the intricate regulation of cellular processes. | ||||||