Ro-31-8220 in solution CAS: 138489-18-6
MF: C25H23N5O2S CH3SO3H
MW: 553.7
A serotonin 1A-receptor agonist used experimentally to test the effects of serotonin.

Ro-31-8220 in solution (CAS 138489-18-6)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 132ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Application: A serotonin 1A-receptor agonist used experimentally to test the effects of serotonin
CAS Number: 138489-18-6
Molecular Weight: 553.7
Molecular Formula: C25H23N5O2S CH3SO3H
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Ro-31-8220 in solution is an inhibitor of GSK-3 β, GRK 5, MKLP-1, p70 S6 Kinase, Pim-1, PKCα, PKC β, PKC ε and PKC γ. Ro-31-8220 is also suggested to be an activator of JNK1.

Formulation :
A 5 mM (1 mg/362 µl) solution of Ro-31-8220 (Cat. No. sc-200619) in H2O
Physical State :
Liquid
Solubility :
Soluble in water (7.3 mg/mL), DMSO (~20 mg/mL), ethanol (5 mM ), DMF (~20 mg/mL), and 1:9 DMF:PBS(pH 7.2) (~0.1 mg/mL).
Storage :
Store at -20° C
Refractive Index :
n20D ~1.74 (Predicted)
IC50 :
PKC α: IC50 = 5 nM; glycogen synthase kinase 3: IC50 = 6.8 nM; PKC: IC50 = 10 nM; PKC βII: IC50 = 14 nM; PKC βI: IC50 = 24 nM; PKC ε: IC50 = 24 nM; PKC γ: IC50 = 27 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
1220
MDL Number :
MFCD03788207
SMILES :
CCCN(CCC)C1CCC2=C(C1)C(=CC=C2)O

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

Ro-31-8220 in solution  Product Citations

See how others have used Ro-31-8220 in solution. Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 27165344  Thomas, L. et al. 2016. Kidney & blood pressure research. 41: 298-310.

PMID: # 31484825  JCI Insight. 4:

Citations 1 to 2 of 2 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 116ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 10ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.