Sept14 Activators
Sept14 Activators comprises various compounds that can indirectly affect the activity or regulation of Sept14. These chemicals interact with different components of the cellular machinery, often impacting the cytoskeleton and cellular signaling pathways. Such compounds may not directly bind to or modify Sept14, but by altering the cellular context in which Sept14 operates, they can lead to changes in its activity.
For example, agents like paclitaxel and nocodazole exert their effects on microtubules, potentially affecting Sept14's role in microtubule organization. Similarly, compounds that modify actin dynamics, such as jasplakinolide, might impact Sept14's interaction with actin structures. Second messenger system modulators like forskolin and PMA can activate downstream kinases, which may phosphorylate septin proteins, including Sept14, thereby modulating their function. Additionally, inhibitors of kinases and phosphatases like ML-7, Y-27632, and calyculin A may influence Sept14 by altering the phosphorylation state of proteins involved in septin filament dynamics.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules and could enhance Sept14 function in microtubule organization. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Stabilizes actin filaments and may indirectly affect Sept14's interaction with the cytoskeleton. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, raising cAMP levels, which can influence various signaling pathways including those involving septins. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C, which can influence septin function in cell division and cytoskeletal dynamics. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
Inhibitor of myosin light chain kinase; altering cytoskeletal dynamics may indirectly engage Sept14 functions. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Inhibits Rho-associated protein kinase (ROCK), potentially impacting Sept14 by altering cytoskeletal organization. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Inhibits glycogen synthase kinase 3 (GSK-3), which may impact septin filament stabilization. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $72.00 $265.00 $495.00 $968.00 | ||
Inhibits myosin II, affecting cytokinesis; Sept14-related processes may be indirectly affected due to its role in cell division. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $163.00 $800.00 | 59 | |
Phosphatase inhibitor; could alter the phosphorylation state of septin proteins, thereby affecting their function. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
Bioactive lipid that acts as a signaling molecule, possibly impacting Sept14 activity related to membrane dynamics. | ||||||