Selenoprotein T (SelT) is a significant protein known for its diverse roles in cellular function, particularly in redox homeostasis and calcium signaling. It is a member of the selenoprotein family, proteins that contain selenium in the form of the amino acid selenocysteine. SelT is prominently expressed in various tissues such as the heart, brain, and muscles, signifying its crucial role in physiological processes.
In the realm of redox homeostasis, SelT is instrumental in protecting cells from oxidative stress by contributing to the antioxidant defense system. Its involvement in calcium signaling is essential for numerous cellular processes, including muscle contraction and cellular communication. Moreover, SelT is also implicated in the regulation of cell proliferation and apoptosis, emphasizing its multifaceted role in cellular integrity and function.Research suggests that SelT has a remarkable impact on the endoplasmic reticulum, where it plays a role in protein folding and the maintenance of calcium homeostasis. Its intricate involvement in various cellular mechanisms underscores its importance in health and disease. Anomalies in the expression and function of SelT have been associated with pathological conditions such as neurodegenerative disorders and cardiovascular diseases. Thus, understanding the biological roles and regulatory mechanisms of SelT can pave the way for new strategies in managing various health conditions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Selenium | 7782-49-2 | sc-250973 | 50 g | $62.00 | 1 | |
May increase SelT due to its role as a source of selenium, essential for selenoprotein synthesis. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
An antioxidant that may upregulate SelT expression to combat oxidative stress. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Could upregulate SelT expression as part of cellular antioxidant defense mechanisms. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
As a metal ion, zinc might modulate SelT expression involved in metal ion homeostasis. | ||||||
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $66.00 $262.00 | 1 | |
Calcium may influence SelT expression involved in calcium signaling pathways. | ||||||
(+)-α-Tocopherol | 59-02-9 | sc-214454 sc-214454A sc-214454B | 10 g 25 g 100 g | $43.00 $62.00 $141.00 | ||
May enhance SelT expression due to its role in antioxidative defense mechanisms. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
As an antioxidant, it could play a role in the induction of SelT expression. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
May enhance SelT expression, supporting cellular redox homeostasis. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
Might induce SelT expression due to its role in cellular antioxidant defenses. | ||||||
Glutathione, reduced | 70-18-8 | sc-29094 sc-29094A | 10 g 1 kg | $82.00 $2091.00 | 8 | |
Could upregulate SelT as part of the cellular response to oxidative stress. | ||||||