Date published: 2026-1-9

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Selenoprotein T Activators

Selenoprotein T (SelT) is a significant protein known for its diverse roles in cellular function, particularly in redox homeostasis and calcium signaling. It is a member of the selenoprotein family, proteins that contain selenium in the form of the amino acid selenocysteine. SelT is prominently expressed in various tissues such as the heart, brain, and muscles, signifying its crucial role in physiological processes.

In the realm of redox homeostasis, SelT is instrumental in protecting cells from oxidative stress by contributing to the antioxidant defense system. Its involvement in calcium signaling is essential for numerous cellular processes, including muscle contraction and cellular communication. Moreover, SelT is also implicated in the regulation of cell proliferation and apoptosis, emphasizing its multifaceted role in cellular integrity and function.Research suggests that SelT has a remarkable impact on the endoplasmic reticulum, where it plays a role in protein folding and the maintenance of calcium homeostasis. Its intricate involvement in various cellular mechanisms underscores its importance in health and disease. Anomalies in the expression and function of SelT have been associated with pathological conditions such as neurodegenerative disorders and cardiovascular diseases. Thus, understanding the biological roles and regulatory mechanisms of SelT can pave the way for new strategies in managing various health conditions.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Selenium

7782-49-2sc-250973
50 g
$62.00
1
(1)

May increase SelT due to its role as a source of selenium, essential for selenoprotein synthesis.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

An antioxidant that may upregulate SelT expression to combat oxidative stress.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Could upregulate SelT expression as part of cellular antioxidant defense mechanisms.

Zinc

7440-66-6sc-213177
100 g
$48.00
(0)

As a metal ion, zinc might modulate SelT expression involved in metal ion homeostasis.

Calcium chloride anhydrous

10043-52-4sc-207392
sc-207392A
100 g
500 g
$66.00
$262.00
1
(1)

Calcium may influence SelT expression involved in calcium signaling pathways.

(+)-α-Tocopherol

59-02-9sc-214454
sc-214454A
sc-214454B
10 g
25 g
100 g
$43.00
$62.00
$141.00
(1)

May enhance SelT expression due to its role in antioxidative defense mechanisms.

L-Ascorbic acid, free acid

50-81-7sc-202686
100 g
$46.00
5
(1)

As an antioxidant, it could play a role in the induction of SelT expression.

N-Acetyl-L-cysteine

616-91-1sc-202232
sc-202232A
sc-202232C
sc-202232B
5 g
25 g
1 kg
100 g
$34.00
$74.00
$270.00
$114.00
34
(1)

May enhance SelT expression, supporting cellular redox homeostasis.

α-Lipoic Acid

1077-28-7sc-202032
sc-202032A
sc-202032B
sc-202032C
sc-202032D
5 g
10 g
250 g
500 g
1 kg
$69.00
$122.00
$212.00
$380.00
$716.00
3
(1)

Might induce SelT expression due to its role in cellular antioxidant defenses.

Glutathione, reduced

70-18-8sc-29094
sc-29094A
10 g
1 kg
$82.00
$2091.00
8
(2)

Could upregulate SelT as part of the cellular response to oxidative stress.