Date published: 2025-12-8

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SDH Inhibitors

Santa Cruz Biotechnology now offers a broad range of SDH Inhibitors for use in various applications. SDH Inhibitors, or Succinate Dehydrogenase inhibitors, are a significant class of chemicals widely utilized in biochemical and agricultural research. These inhibitors play a crucial role in the study of metabolic pathways, particularly the tricarboxylic acid cycle (TCA cycle), also known as the Krebs cycle, by targeting and inhibiting the enzyme succinate dehydrogenase. This enzyme is essential for the oxidation of succinate to fumarate, linking the TCA cycle and the electron transport chain. By modulating this enzyme's activity, SDH Inhibitors provide researchers with valuable tools for probing cellular respiration and energy production processes. In agriculture, these inhibitors are often explored for their potential to enhance plant resistance against certain pathogens by disrupting pathogen metabolism. The versatility of SDH Inhibitors extends to their use in experimental setups aimed at understanding oxidative stress, cellular aging, and metabolic disorders at a molecular level. View detailed information on our available SDH Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Oxaloacetic Acid

328-42-7sc-279934
sc-279934A
sc-279934B
25 g
100 g
1 kg
$300.00
$944.00
$7824.00
1
(0)

Oxaloacetic acid serves as a crucial substrate in the citric acid cycle, facilitating the conversion of carbohydrates, fats, and proteins into energy. Its unique ability to undergo reversible reactions allows it to participate in various metabolic pathways, influencing the kinetics of enzymatic processes. The compound's strong acidic nature promotes effective proton transfer, enhancing its interactions with key enzymes. Additionally, its role as a precursor in amino acid synthesis highlights its importance in cellular metabolism.

Harzianopyridone

126637-69-2sc-280769
sc-280769A
250 µg
1 mg
$82.00
$235.00
1
(0)

Harzianopyridone exhibits unique properties as a selective succinate dehydrogenase (SDH) inhibitor, engaging in specific molecular interactions that disrupt electron transport in cellular respiration. Its structural features allow for distinct binding affinities, influencing reaction kinetics and altering metabolic flux. The compound's ability to modulate redox states within the mitochondria underscores its role in metabolic regulation, showcasing its impact on energy production pathways.