Date published: 2026-4-24

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Harzianopyridone (CAS 126637-69-2)

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CAS Number:
126637-69-2
Molecular Weight:
281.31
Molecular Formula:
C14H19NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Harzianopyridone is an atpenin-related, specific inhibitor of SDH (complex II, succinate-ubiquinone oxidoreductase). Harzianopyridone has garnered attention due to its distinctive chemical structure and wide range of biological activities. Harzianopyridone exhibits properties, including anti-inflammatory, anti-cancer, anti-bacterial, and anti-fungal effects. Harzianopyridone′s ability to impede the growth of pathogenic bacteria and fungi has been thoroughly investigated, alongside its potential as a biopesticide.


Harzianopyridone (CAS 126637-69-2) References

  1. Stereoselective total synthesis of atpenins a4 and b, harzianopyridone, and NBRI23477 B.  |  Ohtawa, M., et al. 2012. Chem Pharm Bull (Tokyo). 60: 898-906. PMID: 22790825
  2. Comparative evaluation of two Trichoderma harzianum strains for major secondary metabolite production and antifungal activity.  |  Ahluwalia, V., et al. 2015. Nat Prod Res. 29: 914-20. PMID: 25248548
  3. Rapid Metabolome and Bioactivity Profiling of Fungi Associated with the Leaf and Rhizosphere of the Baltic Seagrass Zostera marina.  |  Petersen, LE., et al. 2019. Mar Drugs. 17: PMID: 31330983
  4. Iterative Catalysis in the Biosynthesis of Mitochondrial Complex II Inhibitors Harzianopyridone and Atpenin B.  |  Bat-Erdene, U., et al. 2020. J Am Chem Soc. 142: 8550-8554. PMID: 32365298
  5. Crude Citric Acid of Trichoderma asperellum: Tomato Growth Promotor and Suppressor of Fusarium oxysporum f. sp. lycopersici.  |  Al-Askar, AA., et al. 2021. Plants (Basel). 10: PMID: 33498925
  6. Seed Biopriming With Trichoderma Strains Isolated From Tree Bark Improves Plant Growth, Antioxidative Defense System in Rice and Enhance Straw Degradation Capacity.  |  Swain, H., et al. 2021. Front Microbiol. 12: 633881. PMID: 33717027
  7. Ameliorated Antibacterial and Antioxidant Properties by Trichoderma harzianum Mediated Green Synthesis of Silver Nanoparticles.  |  Konappa, N., et al. 2021. Biomolecules. 11: PMID: 33916555
  8. Biosynthesis of the Fusarium Mycotoxin (-)-Sambutoxin.  |  Go, EB., et al. 2021. Org Lett. 23: 7819-7823. PMID: 34581588
  9. Harzianopyridone Supplementation Reduced Chromium Uptake and Enhanced Activity of Antioxidant Enzymes in Vigna radiata Seedlings Exposed to Chromium Toxicity.  |  Shah, AA., et al. 2022. Front Plant Sci. 13: 881561. PMID: 35860543
  10. Dual inhibition of the Echinococcus multilocularis energy metabolism.  |  Chaudhry, S., et al. 2022. Front Vet Sci. 9: 981664. PMID: 35990276
  11. Antibacterial activity of peptaibols from Trichoderma longibrachiatum SMF2 against gram-negative Xanthomonas oryzae pv. oryzae, the causal agent of bacterial leaf blight on rice.  |  Zhang, YQ., et al. 2022. Front Microbiol. 13: 1034779. PMID: 36304956
  12. Spores of Trichoderma Strains over P. vulgaris Beans: Direct Effect on Insect Attacks and Indirect Effect on Agronomic Parameters.  |  Rodríguez-González, Á., et al. 2022. Insects. 13: PMID: 36554996
  13. Trichoderma pubescens Elicit Induced Systemic Resistance in Tomato Challenged by Rhizoctonia solani.  |  Behiry, S., et al. 2023. J Fungi (Basel). 9: PMID: 36836282
  14. Circulating metabolites as potential biomarkers for the early detection and prognosis surveillance of gastrointestinal cancers.  |  Song, G., et al. 2023. Metabolomics. 19: 36. PMID: 37014438

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Harzianopyridone, 250 µg

sc-280769
250 µg
$82.00

Harzianopyridone, 1 mg

sc-280769A
1 mg
$235.00