SA-2 Activators
SA-2 activators represent a specific chemical class of compounds designed to interact with and modulate the activity of SA-2, a protein whose precise function has garnered significant interest in the field of molecular biology. SA-2, short for "Structural Maintenance of Chromosomes 2," is a member of the Structural Maintenance of Chromosomes (SMC) family of proteins. These proteins are known for their pivotal roles in maintaining the structural integrity and organization of chromosomes within the nucleus of eukaryotic cells. SA-2, in particular, plays an essential role in chromosome condensation, segregation, and organization during various cellular processes, such as mitosis and meiosis.
SA-2 activators exert their influence by interacting with SA-2 at a molecular level. These compounds can either enhance or inhibit the activity of SA-2, leading to alterations in chromosomal structure and organization. The modulation of SA-2 activity can have significant consequences for the fidelity of chromosome segregation, gene expression, and the overall stability of the genome. Researchers studying SA-2 activators aim to unravel the intricate details of SA-2's functions within the cell, shedding light on the molecular mechanisms governing chromosome dynamics. Understanding the roles and regulation of SA-2 in chromosomal maintenance is essential for advancing our knowledge of fundamental cellular processes, such as cell division and genome stability, and their implications for various biological contexts.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
A selective histone deacetylase inhibitor, affecting chromatin structure and potentially influencing cohesin complex dynamics. | ||||||
A-485 | 1889279-16-6 | sc-507493 | 5 mg | $275.00 | ||
A potent and selective catalytic inhibitor of p300/CBP histone acetyltransferases, influencing chromatin remodeling and possibly cohesin function. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
A BET bromodomain inhibitor, affects chromatin structure and gene expression, potentially impacting cohesin complex activity. | ||||||
I-CBP112 | 1640282-31-0 | sc-507494 | 25 mg | $400.00 | ||
A selective CBP/p300 bromodomain inhibitor, potentially influencing chromatin structure and cohesin function. | ||||||
RGFP966 | 1357389-11-7 | sc-507300 | 5 mg | $115.00 | ||
A selective histone deacetylase 3 (HDAC3) inhibitor, indirectly affecting chromatin architecture and possibly cohesin function. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $265.00 $944.00 | 5 | |
A selective p300/CBP histone acetyltransferase inhibitor, could affect chromatin remodeling and cohesin dynamics. | ||||||
JNJ-26481585 | 875320-29-9 | sc-364515 sc-364515A | 5 mg 50 mg | $321.00 $1224.00 | ||
A potent pan-histone deacetylase inhibitor, potentially affecting chromatin structure and cohesin dynamics. | ||||||
(S)-2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetamide | 202590-98-5 | sc-501130 | 2.5 mg | $330.00 | ||
A BET bromodomain inhibitor, potentially influencing gene expression and chromatin architecture related to cohesin function. | ||||||