RyR Activators
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Heparin, Lithium Salt | 9045-22-1 | sc-203997 sc-203997A sc-203997B | 100 KU 500 KU 1000 KU | $143.00 $510.00 $969.00 | 5 | |
Heparin, Lithium Salt exhibits unique properties as a RyR modulator, primarily through its intricate binding dynamics with calcium channels. This compound facilitates calcium release by stabilizing the open conformation of the receptor, enhancing ion flux. Its high charge density promotes strong electrostatic interactions, while its structural flexibility allows for conformational adaptability. These characteristics influence the kinetics of calcium signaling pathways, impacting cellular excitability and muscle contraction. | ||||||
Heparin sodium salt | 9041-08-1 | sc-203075 sc-203075A sc-203075B sc-203075C sc-203075D sc-203075E sc-203075F | 250 mg 1 g 5 g 25 g 100 g 500 g 1 kg | $79.00 $205.00 $699.00 $3472.00 $13773.00 $40290.00 $69360.00 | 23 | |
Heparin sodium salt acts as a RyR modulator by engaging in specific interactions with the receptor's binding sites, promoting calcium ion release. Its unique sulfated glycosaminoglycan structure enhances affinity for positively charged residues, facilitating conformational changes in the receptor. This compound's ability to form transient complexes with RyR influences the kinetics of calcium release, thereby modulating intracellular calcium levels and affecting cellular signaling cascades. | ||||||