Date published: 2026-4-28

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RXR gamma Activators

Santa Cruz Biotechnology now offers a broad range of RXR gamma Activators for use in various applications. RXR gamma Activators are compounds that modulate the activity of the Retinoid X Receptor gamma, a nuclear receptor that plays a critical role in gene expression regulation. In scientific research, RXR gamma Activators are vital tools for studying the transcriptional control mechanisms that govern cellular differentiation, metabolism, and apoptosis. These activators are particularly significant in fields like molecular biology and biochemistry, where they are used to unravel the complexities of nuclear receptor signaling pathways. By interacting with RXR gamma, these compounds can help explain the receptor's role in lipid metabolism, immune response, and developmental processes. Researchers also use RXR gamma Activators to explore receptor heterodimerization, where RXR partners with other nuclear receptors, influencing the expression of a wide array of genes. The availability of these activators enhances our understanding of cellular processes and aids in the development of new experimental models. View detailed information on our available RXR gamma Activators by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Bexarotene

153559-49-0sc-217753
sc-217753A
10 mg
100 mg
$55.00
$250.00
6
(1)

Used clinically for the therapeutic purposes helping with cutaneous T-cell lymphoma, bexarotene is a synthetic RXR agonist.

9-cis-Retinoic acid

5300-03-8sc-205589
sc-205589B
sc-205589C
sc-205589D
sc-205589A
1 mg
25 mg
250 mg
500 mg
5 mg
$71.00
$424.00
$3121.00
$5722.00
$148.00
10
(1)

This is a natural ligand for RXRs. It is also termed alitretinoin.

LG 100268

153559-76-3sc-211737
5 mg
$390.00
2
(1)

A potent and selective RXR agonist that has been extensively studied for its effects on lipid metabolism and cancer.

Bexarotene d4

2182068-00-2sc-353071
10 mg
$4000.00
(0)

Bexarotene d4 acts as a selective RXR gamma modulator, characterized by its capacity to stabilize receptor dimers through unique ligand-receptor interactions. This compound exhibits a distinct binding affinity that alters the receptor's conformational dynamics, leading to enhanced transcriptional activity. Its unique hydrophobic characteristics contribute to its interaction with lipid membranes, influencing cellular localization and distribution. Additionally, Bexarotene d4 demonstrates notable stability in various environments, impacting its reactivity and interaction with downstream signaling molecules.

SR 11237

146670-40-8sc-296418
sc-296418A
5 mg
50 mg
$211.00
$877.00
(0)

This is a potent RXR agonist that has demonstrated anticancer activity in research models.