Date published: 2025-12-20

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RUSC2 Inhibitors

RUSC2 inhibitors are a category of chemical compounds designed to target and modulate the activity of RUSC2, a protein encoded by the RUN and SH3 domain-containing 2 gene. These inhibitors are a subject of interest in the field of molecular biology and pharmacology due to the critical roles that RUSC2 plays in various cellular processes. RUSC2, also known as IPCEF1 (Interactor Protein for Cytohesin Exchange Factors 1), is a multi-functional protein involved in intracellular signaling and trafficking events. Its primary function revolves around regulating the dynamics of membrane-associated processes, such as endocytosis and vesicle transport, which are pivotal for cellular homeostasis.

RUSC2 inhibitors typically act by interfering with the binding of RUSC2 to its interaction partners or by modulating its enzymatic activity, depending on the specific mechanism of action. These inhibitors can serve as valuable tools in research to better understand the intricate roles of RUSC2 in cellular functions. They are also explored for regulating cellular processes that rely on RUSC2 activity.

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