Date published: 2026-3-3

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Rtl1 Activators

Rtl1 activators are a category of compounds that target the protein Retrotransposon-like 1 (Rtl1), which is thought to play a role in various cellular processes, possibly including the regulation of gene expression and the modulation of signal transduction pathways. The regulation and activation of Rtl1 are not fully understood and are the subject of ongoing research efforts. As an activator, a compound would enhance the activity or increase the expression of Rtl1 within the cellular context.

Direct activators of Rtl1 would likely interact with the protein at specific sites to promote its activity. This interaction could lead to conformational changes in Rtl1 that either enhance its ability to interact with other proteins or with DNA, or increase its catalytic activity if it possesses enzymatic function. These activators might mimic endogenous ligands or substrates of Rtl1, or they might stabilize the active form of the protein, making it more effective in carrying out its cellular roles. Indirect activators of Rtl1 could function by influencing the cellular signaling pathways that regulate the protein's expression or activity. This might involve the modulation of upstream transcription factors that control the Rtl1 gene, leading to increased production of the protein. Alternatively, compounds could affect post-translational modifications of Rtl1, thereby altering its stability, localization, or activity. Indirect activators might also impact the levels of cofactors or partner proteins required for Rtl1 function, thereby enhancing its activity.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Pioglitazone

111025-46-8sc-202289
sc-202289A
1 mg
5 mg
$55.00
$125.00
13
(1)

Pioglitazone is a PPARγ agonist. PPARγ, a nuclear receptor, is involved in the regulation of lipid and glucose metabolism. Activation of PPARγ by Pioglitazone can lead to changes in the cellular environment that favor the functional activity of Rtl1, a protein involved in metabolic processes.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol is a natural polyphenol that can activate SIRT1, a NAD+-dependent deacetylase. SIRT1 has been shown to influence a variety of metabolic processes, and its activation can enhance the functional activity of Rtl1.

Metformin-d6, Hydrochloride

1185166-01-1sc-218701
sc-218701A
sc-218701B
1 mg
5 mg
10 mg
$292.00
$822.00
$1540.00
1
(1)

Metformin activates AMP-activated protein kinase (AMPK), a key regulator of energy homeostasis. Activation of AMPK can alter metabolic pathways favorably for the functional activity of Rtl1.

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$65.00
$280.00
$400.00
48
(2)

AICAR is an analog of AMP that can activate AMPK, a key regulator of energy homeostasis. Activation of AMPK can alter the metabolic pathways favorably for the functional activity of Rtl1.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Dexamethasone is a glucocorticoid receptor agonist. Activation of the glucocorticoid receptor can alter gene expression profiles and metabolic processes in a way that enhances the functional activity of Rtl1.

GW 9662

22978-25-2sc-202641
5 mg
$70.00
30
(2)

GW1929 is a PPARγ agonist. Activation of PPARγ can lead to changes in the cellular environment that favor the functional activity of Rtl1, a protein involved in metabolic processes.

Exendin-4

141758-74-9sc-474611
sc-474611A
500 µg
1 mg
$146.00
$198.00
1
(0)

Exendin-4 is a GLP-1 receptor agonist. GLP-1 receptor activation can lead to changes in glucose metabolism and insulin secretion that can enhance the functional activity of Rtl1.

Rosiglitazone

122320-73-4sc-202795
sc-202795A
sc-202795C
sc-202795D
sc-202795B
25 mg
100 mg
500 mg
1 g
5 g
$120.00
$326.00
$634.00
$947.00
$1259.00
38
(1)

Rosiglitazone is a PPARγ agonist. Activation of PPARγ can lead to changes in the cellular environment that favor the functional activity of Rtl1, a protein involved in metabolic processes.

Berberine

2086-83-1sc-507337
250 mg
$92.00
1
(0)

Berberine has been shown to activate AMPK, a key regulator of energy homeostasis. Activation of AMPK can alter metabolic pathways favorably for the functional activity of Rtl1.

Fenofibrate

49562-28-9sc-204751
5 g
$41.00
9
(1)

Fenofibrate is a PPARα agonist. Activation of PPARα can alter lipid metabolism in a way that enhances the functional activity of Rtl1.