Ros Activators
The class of ROS activators comprises a diverse range of chemicals that exert their effects through distinct mechanisms, contributing to the activation of cellular defenses against reactive oxygen species (ROS). Quercetin, a flavonoid, activates the Nrf2-antioxidant response element (ARE) pathway, enhancing the expression of antioxidant enzymes. This indirect method promotes an enhanced cellular antioxidant capacity, showcasing Quercetin as a modulator of antioxidant pathways. Resveratrol, known for its presence in red wine, activates SIRT1, a deacetylase involved in cellular stress responses. By activating SIRT1, Resveratrol indirectly enhances cellular stress resistance, contributing to the activation of defenses against ROS. Lycopene, a carotenoid found in tomatoes, directly scavenges free radicals, including ROS, highlighting its role as a direct activator of cellular antioxidant defenses. Alpha-lipoic acid activates the Nrf2-ARE pathway, similar to Quercetin, contributing to the upregulation of antioxidant enzymes and enhancing the cellular antioxidant capacity. Naringenin and EGCG, compounds found in citrus fruits and green tea, respectively, also activate the Nrf2-ARE pathway, emphasizing the importance of this pathway in cellular responses to oxidative stress.
Melatonin, a hormone involved in circadian rhythms, directly scavenges various free radicals, including ROS, acting as a direct activator of cellular antioxidant defenses. Curcumin, found in turmeric, activates the Nrf2-ARE pathway, modulating cellular antioxidant pathways and enhancing defenses against ROS. Astaxanthin, a potent antioxidant found in algae and seafood, directly scavenges ROS, contributing to the direct activation of cellular antioxidant defenses. Carnosic acid, present in rosemary, activates the Nrf2-ARE pathway, similar to Quercetin and Alpha-lipoic acid, enhancing the expression of antioxidant enzymes. Selenium, an essential trace element, directly contributes to the activation of cellular defenses against ROS by being a crucial component of antioxidant enzymes. Trolox, a water-soluble analog of vitamin E, acts as a direct activator by scavenging various free radicals, including ROS.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin activates the Nrf2-antioxidant response element (ARE) pathway, enhancing the expression of antioxidant enzymes. By upregulating cellular antioxidants, Quercetin provides an indirect method of activating ROS defenses, promoting an enhanced cellular antioxidant capacity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol activates SIRT1, a deacetylase involved in cellular stress responses. By activating SIRT1, Resveratrol promotes deacetylation of various targets, leading to increased cellular stress resistance, which indirectly contributes to the activation of cellular defenses against ROS. | ||||||
Lycopene | 502-65-8 | sc-205738 sc-205738A sc-205738B | 1 mg 5 mg 1 g | $143.00 $571.00 $6125.00 | 4 | |
Lycopene is a potent antioxidant that scavenges free radicals, including ROS. By directly neutralizing ROS, Lycopene acts as a direct activator of cellular antioxidant defenses, preventing oxidative stress. Its ability to directly scavenge ROS showcases Lycopene as a direct activator of cellular defenses against oxidative damage. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
Alpha-lipoic acid is an antioxidant that activates Nrf2-ARE pathway, enhancing the expression of antioxidant enzymes. By upregulating cellular antioxidants, Alpha-lipoic acid provides an indirect method of activating ROS defenses, promoting an enhanced cellular antioxidant capacity. | ||||||
Naringenin | 480-41-1 | sc-219338 | 25 g | $245.00 | 11 | |
Naringenin activates the Nrf2-antioxidant response element (ARE) pathway, enhancing the expression of antioxidant enzymes. By upregulating cellular antioxidants, Naringenin provides an indirect method of activating ROS defenses, promoting an enhanced cellular antioxidant capacity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG activates the Nrf2-antioxidant response element (ARE) pathway, enhancing the expression of antioxidant enzymes. By upregulating cellular antioxidants, EGCG provides an indirect method of activating ROS defenses, promoting an enhanced cellular antioxidant capacity. | ||||||
Melatonin | 73-31-4 | sc-207848 sc-207848A sc-207848B sc-207848C sc-207848D sc-207848E | 1 g 5 g 25 g 100 g 250 g 1 kg | $64.00 $72.00 $214.00 $683.00 $1173.00 $3504.00 | 16 | |
Melatonin is an antioxidant that scavenges various free radicals, including ROS. By directly neutralizing ROS, Melatonin acts as a direct activator of cellular antioxidant defenses, preventing oxidative stress. Its ability to directly scavenge ROS showcases Melatonin as a direct activator of cellular defenses against oxidative damage. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin activates the Nrf2-antioxidant response element (ARE) pathway, enhancing the expression of antioxidant enzymes. By upregulating cellular antioxidants, Curcumin provides an indirect method of activating ROS defenses, promoting an enhanced cellular antioxidant capacity. | ||||||
Carnosic acid | 3650-09-7 | sc-202520 sc-202520A | 10 mg 50 mg | $60.00 $165.00 | 6 | |
Carnosic acid activates the Nrf2-antioxidant response element (ARE) pathway, enhancing the expression of antioxidant enzymes. By upregulating cellular antioxidants, Carnosic acid provides an indirect method of activating ROS defenses, promoting an enhanced cellular antioxidant capacity. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $61.00 | 1 | |
Selenium is an essential trace element that forms part of antioxidant enzymes, such as glutathione peroxidase. By being a crucial component of these enzymes, Selenium directly contributes to the activation of cellular defenses against ROS, highlighting its role as a direct activator in maintaining cellular redox balance. | ||||||