RNFT1 Inhibitors
RNFT1 inhibitors includes kinase inhibitors such as Staurosporine, which can influence the phosphorylation state of RNFT1, thereby modulating its functional activity and protein stability. LY294002 and Wortmannin act upstream within the PI3K/Akt signaling pathway, where their inhibition can indirectly affect the regulation of RNFT1. The MEK inhibitor PD98059 and p38 MAPK inhibitor SB203580 can adjust RNFT1 activity by altering the MAPK/ERK and stress response pathways. U73122 disrupts phospholipase C activity, impacting second messenger systems that can regulate RNFT1, while the calcium chelator BAPTA can modulate calcium-dependent processes linked to RNFT1 function.
SP600125, targeting JNK, can influence RNFT1 through stress-activated protein kinase pathways. MG132 can alter RNFT1 activity by preventing the degradation of regulatory proteins that control its function. ZM-447439, an Aurora kinase inhibitor, can indirectly affect RNFT1 during cell cycle progression. Rapamycin, an mTOR inhibitor, can alter RNFT1 regulation through the mTORC1 signaling pathway, and NF449, a G-protein antagonist, can disrupt G-protein coupled signaling pathways that involve RNFT1.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Inhibits protein kinases which can regulate RNFT1 phosphorylation state, affecting its activity and stability. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, upstream of Akt, affecting RNFT1 regulation by PI3K/Akt signaling pathway. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Alters cellular signaling by PI3K inhibition, impacting RNFT1 function indirectly. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK, affecting the MAPK/ERK pathway that may be involved in RNFT1 regulation. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Targets p38 MAPK, potentially altering RNFT1 activity through stress response pathways. | ||||||
BAPTA, Free Acid | 85233-19-8 | sc-201508 sc-201508A | 100 mg 500 mg | $67.00 $262.00 | 10 | |
Calcium chelator, could alter calcium-dependent regulation of RNFT1. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, possibly affecting RNFT1 function through stress-activated protein kinase pathways. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Proteasome inhibitor, can stabilize proteins that negatively regulate RNFT1. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
Aurora kinase inhibitor, affects cell cycle progression, indirectly influencing RNFT1 function. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor, can affect RNFT1 by altering mTORC1 signaling pathway. | ||||||