RNF20 Activators
The chemical class of RNF20 activators comprises compounds that indirectly influence the activity of RNF20, primarily through modulation of chromatin structure and histone modifications. This group includes various histone deacetylase (HDAC) inhibitors, such as Trichostatin A, Vorinostat, Valproic Acid, MS-275 (Entinostat), Sodium Butyrate, SAHA (Vorinostat), and RGFP966. These compounds exert their influence by altering the acetylation status of histones, thus impacting chromatin accessibility and potentially enhancing the role of RNF20 in histone ubiquitination and gene regulation.
In addition to HDAC inhibitors, this class encompasses inhibitors of histone methyltransferases like BIX-01294, Methylstat, and UNC0638, as well as the p300/CBP histone acetyltransferase inhibitor C646. These compounds modulate histone methylation and acetylation patterns, respectively, thereby influencing the chromatin landscape in which RNF20 operates. By altering the histone modification status, these compounds indirectly affect RNF20's activity in chromatin remodeling and transcriptional regulation.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor; can indirectly influence RNF20 by altering chromatin structure, potentially enhancing its role in histone modification. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor; might affect RNF20 indirectly by changing the transcriptional landscape and chromatin accessibility. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Another HDAC inhibitor; can modulate RNF20 activity indirectly through effects on chromatin remodeling and gene expression. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
An HDAC inhibitor; may influence RNF20 by affecting chromatin structure and histone modifications. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
A selective HDAC inhibitor; could indirectly modulate RNF20 activity by altering histone acetylation patterns. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
An HDAC inhibitor; can impact RNF20 indirectly by influencing chromatin dynamics and transcription regulation. | ||||||
BIX01294 hydrochloride | 1392399-03-9 | sc-293525 sc-293525A sc-293525B | 1 mg 5 mg 25 mg | $36.00 $110.00 $400.00 | ||
A G9a histone methyltransferase inhibitor; might affect RNF20 indirectly by modulating histone methylation and chromatin structure. | ||||||
Methylstat | 1310877-95-2 | sc-507374 | 10 mg | $480.00 | ||
An inhibitor of histone methyltransferases; can indirectly influence RNF20 activity by affecting chromatin modifications. | ||||||
UNC0638 | 1255580-76-7 | sc-397012 | 10 mg | $315.00 | ||
A selective inhibitor of G9a and GLP histone methyltransferases; potentially modulates RNF20 through changes in chromatin architecture. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $260.00 $925.00 | 5 | |
A selective p300/CBP histone acetyltransferase inhibitor; can indirectly affect RNF20 through histone acetylation modifications. | ||||||