RNF113B Activators

RNF113B Activators can be understood as chemicals that indirectly influence the activity of RNF113B, a protein involved in the DNA damage response and the ubiquitin-proteasome system. These compounds generally function either by causing DNA damage, thereby inducing the DNA damage response involving RNF113B, or by inhibiting the proteasome, thereby potentially affecting the ubiquitin-proteasome system involving RNF113B. For instance, hydroxyurea, doxorubicin, cisplatin, etoposide, camptothecin, and bleomycin can induce DNA damage, thereby potentially inducing the DNA damage response involving RNF113B. Moreover, MG132, bortezomib, carfilzomib, MLN2238, epoxomicin, and marizomib function by inhibiting the proteasome, thereby potentially affecting the ubiquitin-proteasome system involving RNF113B.