RKIP Activators
RKIP Activators, short for Raf Kinase Inhibitory Protein Activators, represent a class of chemical compounds that hold significance in the realm of cellular signaling and molecular biology. These molecules are characterized by their ability to modulate the activity of Raf Kinase Inhibitory Protein (RKIP), a crucial regulator in intracellular signaling pathways. RKIP, also known as phosphatidylethanolamine-binding protein 1 (PEBP1), plays a pivotal role in cellular processes by influencing the phosphorylation status and activation of various protein kinases, particularly those involved in the mitogen-activated protein kinase (MAPK) pathway. RKIP Activators, through their interaction with RKIP, can fine-tune the cellular responses to extracellular signals, thereby impacting cell fate and function.
At the molecular level, RKIP Activators exhibit the capacity to bind to RKIP and alter its conformation, leading to changes in its phosphorylation state and its ability to interact with other signaling proteins. This modulation of RKIP's activity has downstream effects on the MAPK signaling cascade, which is implicated in diverse cellular functions, including cell growth, differentiation, and survival. By targeting RKIP, these chemical compounds serve as valuable tools for researchers seeking to unravel the intricacies of signal transduction pathways and their implications in various physiological and pathological conditions.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is a natural polyphenol found in grapes and berries. It is known to activate SIRT1, leading to deacetylation of various proteins and potentially enhancing RKIP expression as part of a cellular stress response, aiming to maintain cellular integrity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, the main active ingredient in turmeric, has been reported to upregulate RKIP expression. It modulates various signaling pathways, potentially stabilizing cellular functions and acting as a protective agent against stress and damage. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Found in cruciferous vegetables, sulforaphane is known for its antioxidant properties. It may enhance RKIP expression by modulating the Nrf2 pathway, contributing to cellular defense mechanisms against oxidative stress. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid with antioxidant properties. It is thought to induce RKIP expression by modulating signaling pathways related to inflammation and oxidative stress, potentially aiding in the stabilization of cellular functions. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a major component of green tea with known antioxidant properties. It is suggested to upregulate RKIP as part of a broader cellular protective mechanism against oxidative damage and inflammation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A derivative of vitamin A, retinoic acid plays a vital role in cell growth and differentiation. It is thought to modulate RKIP expression through retinoid receptors, contributing to cellular regulation and potentially acting as a protective agent against cellular stress. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $62.00 | 1 | |
An essential trace element, selenium is known for its antioxidant properties. It may induce RKIP expression by contributing to the cellular antioxidant defense system, helping to maintain cellular integrity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein is a soy-derived isoflavone with known antioxidant properties. It is suggested to modulate various signaling pathways, potentially upregulating RKIP expression and contributing to cellular protection and stability. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc is an essential mineral crucial for numerous biological processes. It is thought to induce RKIP expression through its role in enzyme function and cellular signaling, potentially acting as a stabilizing agent within the cell. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine is a natural stimulant found in coffee and tea. It is suggested to influence cellular signaling and stress response mechanisms, potentially upregulating RKIP as part of a broader cellular adaptive response to maintain stability and functionality. | ||||||