Ribosomal Protein L8 Activators
"RPL8 Activators," are compounds that can indirectly influence RPL8, a crucial ribosomal protein, by modulating related cellular processes or pathways. RPL8 can be influenced by altering transcriptional regulation, ribosome biogenesis, and protein synthesis, given its inherent role in the cellular machinery responsible for protein synthesis. For instance, 5-Azacytidine and Trichostatin A can affect the expression of RPL8 by modulating DNA methyltransferase and histone deacetylase, respectively, thereby altering the transcriptional landscape within the cell. Moreover, compounds such as CX-5461, by inhibiting RNA polymerase I, can have repercussions on ribosomal RNA synthesis, subsequently affecting the incorporation of RPL8 into ribosomes.
Similarly, compounds like Rapamycin and Torin 1, which are mTOR inhibitors, can impact protein synthesis, thereby indirectly modulating RPL8 activity. The interaction with mTOR signaling translates to alterations in the translation process where RPL8 plays a significant role. Additionally, other compounds like Resveratrol and Curcumin, known for their multifarious effects on cellular signaling and metabolism, can exert indirect influence on ribosomal proteins including RPL8.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
May modify RPL8 expression through inhibition of DNA methyltransferase, altering gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
By inhibiting histone deacetylase, it could theoretically alter RPL8 expression. | ||||||
CX-5461 | 1138549-36-6 | sc-507275 | 5 mg | $240.00 | ||
Potentially affects RPL8 by inhibiting RNA polymerase I, impacting ribosomal RNA synthesis. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Binds DNA and inhibits RNA synthesis which could indirectly impact RPL8 due to decreased ribosome biogenesis. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR, potentially affecting protein synthesis and indirectly impacting RPL8 activity. | ||||||
Torin 1 | 1222998-36-8 | sc-396760 | 10 mg | $240.00 | 7 | |
ATP-competitive mTOR inhibitor, can indirectly impact ribosomal protein activity by modulating protein synthesis. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $51.00 $123.00 $178.00 | 11 | |
Inhibits protein synthesis which may indirectly affect RPL8’s activity in the ribosome. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Inhibits protein synthesis by blocking peptide bond formation, potentially affecting RPL8 activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Has various effects on cellular signaling and metabolism and might have indirect effects on ribosomal proteins. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Influences various cellular processes and might indirectly impact RPL8. | ||||||