RGPD7 inhibitors constitute a specialized chemical class designed to selectively modulate the activity of the RNA-binding G-patch domain-containing protein 7 (RGPD7). RGPD7 is a member of the RGPD family, which is known for its involvement in RNA processing and regulation. The inhibitors developed for RGPD7 are characterized by a specific chemical structure that allows them to interact selectively with defined binding sites on the RGPD7 protein, thereby influencing its molecular activities at the RNA level. This tailored design is critical for ensuring a high degree of specificity, preventing unintended effects on other cellular components or RNA-binding proteins.
The mechanism of action of RGPD7 inhibitors involves disrupting the normal functioning of the RGPD7 protein, potentially impacting RNA processing events and regulatory pathways. The selectivity of these inhibitors is essential to avoid interference with other closely related RNA-binding proteins. As researchers delve into the complexities of RNA biology and regulatory networks, RGPD7 inhibitors serve as valuable tools for unraveling the precise molecular mechanisms governed by RGPD7. The study of this chemical class contributes to a deeper understanding of the role played by RGPD7 in cellular physiology, offering insights into its potential functions within the intricate networks that regulate RNA processing and gene expression. Overall, the exploration of RGPD7 inhibitors provides a platform for advancing our understanding of the molecular landscape surrounding RNA-mediated processes within the cellular context.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Sirolimus is an mTOR inhibitor which could decrease protein synthesis and potentially downregulate RGPD7 expression. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Cycloheximide can inhibit eukaryotic protein synthesis by preventing translational elongation, potentially reducing RGPD7 levels. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA, inhibiting RNA polymerase action and potentially suppressing RGPD7 mRNA transcription. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide has been shown to inhibit the transcription of a wide range of genes and may reduce RGPD7 expression. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Bortezomib is a proteasome inhibitor which may lead to reduced protein levels, including those of RGPD7, by preventing protein degradation. | ||||||
R788 | 901119-35-5 | sc-364597 sc-364597A | 2 mg 50 mg | $405.00 $4000.00 | 2 | |
As a kinase inhibitor, R788 could affect signal transduction pathways that regulate RGPD7 gene expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
This compound inhibits PI3K and could downregulate protein synthesis including that of RGPD7 through various signaling pathways. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol is a CDK inhibitor that could alter cell cycle progression and potentially downregulate RGPD7 expression. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $315.00 | ||
Palbociclib selectively inhibits CDK4/6, which might influence the cell cycle and reduce RGPD7 expression indirectly. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $56.00 $212.00 $764.00 | 24 | |
Nutlin-3 disrupts the interaction between p53 and MDM2, which could lead to changes in gene expression profiles, including RGPD7. | ||||||