REDD-2 Inhibitors
The group of chemicals known as REDD-2 Inhibitors predominantly focuses on the modulation of the mTOR signaling pathway, considering REDD-2's association with this pathway. By targeting mTOR directly, these chemicals can indirectly modulate the functional aspects of REDD-2 within the cell. mTOR, an integral kinase in cellular metabolism, growth, and survival, exists in two complexes: mTORC1 and mTORC2. By influencing the activities of these complexes, the REDD-2 inhibitors can cast a profound impact on cellular responses, especially under stress conditions.
The chemicals listed predominantly inhibit either one or both mTOR complexes, thus playing a crucial role in suppressing or modulating the downstream effects where REDD-2 might have its function. It's essential to recognize that while the direct inhibition of REDD-2 remains to be extensively explored, these mTOR pathway modulators offer valuable insights into how REDD-2 function can be influenced indirectly.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor, it suppresses mTORC1 activity. As REDD-2 is associated with mTOR signaling, its function can be impacted by rapamycin. | ||||||
Torin 1 | 1222998-36-8 | sc-396760 | 10 mg | $245.00 | 7 | |
A potent mTOR inhibitor. It inhibits both mTORC1 and mTORC2 and can influence REDD-2 by modulating mTOR activity. | ||||||
AZD8055 | 1009298-09-2 | sc-364424 sc-364424A | 10 mg 50 mg | $163.00 $352.00 | 12 | |
A selective mTOR inhibitor that impacts both mTORC1 and mTORC2, potentially influencing REDD-2's role in the pathway. | ||||||
PP242 | 1092351-67-1 | sc-301606A sc-301606 | 1 mg 5 mg | $57.00 $172.00 | 8 | |
Inhibits mTORC1 and mTORC2, thereby can affect the signaling processes associated with REDD-2. | ||||||
KU 0063794 | 938440-64-3 | sc-361219 | 10 mg | $209.00 | ||
mTOR inhibitor affecting both complexes, mTORC1 and mTORC2, indirectly modulating REDD-2's function within the pathway. | ||||||
PI-103 | 371935-74-9 | sc-203193 sc-203193A | 1 mg 5 mg | $33.00 $131.00 | 3 | |
Inhibits PI3K and mTOR, thus, given the linkage of REDD-2 with mTOR signaling, PI-103 can indirectly influence REDD-2. | ||||||
Everolimus | 159351-69-6 | sc-218452 sc-218452A | 5 mg 50 mg | $131.00 $651.00 | 7 | |
Derivative of Rapamycin, inhibits mTOR, thereby affecting pathways linked with REDD-2. | ||||||
BEZ235 | 915019-65-7 | sc-364429 | 50 mg | $211.00 | 8 | |
Dual PI3K and mTOR inhibitor. By targeting these pathways, it can indirectly modulate the role of REDD-2. | ||||||
Ridaforolimus | 572924-54-0 | sc-212783 | 5 mg | $248.00 | 1 | |
mTOR inhibitor; through mTOR modulation, it can influence cellular processes associated with REDD-2. | ||||||
WYE-125132 | 1144068-46-1 | sc-364651 sc-364651A | 10 mg 50 mg | $510.00 $1536.00 | ||
mTOR inhibitor that impacts both mTORC1 and mTORC2, potentially affecting REDD-2's function within the pathway. | ||||||