RBMY1 Inhibitors
RBMY1 inhibitors belong to a specialized chemical class characterized by their capacity to modulate the function of the RNA-binding motif Y-linked family 1 (RBMY1) protein. The RBMY1 protein is a member of the RNA recognition motif (RRM) family, playing a pivotal role in RNA metabolism and gene expression regulation. Structurally, RBMY1 inhibitors are designed to interact with specific binding sites on the RBMY1 protein, thereby altering its conformation and impeding its ability to effectively bind to target RNA molecules. This targeted interference serves as the basis for their classification within the broader realm of RNA-binding protein inhibitors.
RBMY1 inhibitors are meticulously crafted to ensure a high degree of selectivity for the RBMY1 protein, minimizing off-target effects. These inhibitors often possess distinct molecular motifs that facilitate their precise interaction with key residues on the RBMY1 protein, disrupting its normal RNA-binding function. The development of RBMY1 inhibitors represents a significant stride in the realm of molecular biology, shedding light on the intricate mechanisms governing post-transcriptional gene regulation.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Leptomycin B | 87081-35-4 | sc-358688 sc-358688A sc-358688B | 50 µg 500 µg 2.5 mg | $105.00 $408.00 $1224.00 | 35 | |
Leptomycin B is an inhibitor of nuclear export. It binds to exportin 1 (CRM1) and can disrupt the nuclear export of RNA-binding proteins, potentially influencing proteins like RBMY1. | ||||||
PAC 1 | 315183-21-2 | sc-203174 sc-203174A | 10 mg 50 mg | $129.00 $525.00 | 1 | |
PhenDC3 is a small molecule that can bind to G-quadruplexes, secondary structures found in nucleic acids. It may affect RNA-protein interactions, potentially altering RBMY1's function. | ||||||
Silvestrol | 697235-38-4 | sc-507504 | 1 mg | $920.00 | ||
Silvestrol is an inhibitor of the eukaryotic initiation factor 4A (eIF4A), a component of the translation initiation complex. By influencing translation, it can indirectly affect RNA-binding proteins. | ||||||
Emetine | 483-18-1 | sc-470668 sc-470668A sc-470668B sc-470668C | 1 mg 10 mg 50 mg 100 mg | $352.00 $566.00 $1331.00 $2453.00 | ||
Emetine is an alkaloid that inhibits protein synthesis. By generally suppressing protein translation, it can indirectly influence the function of RNA-binding proteins. | ||||||
CX-5461 | 1138549-36-6 | sc-507275 | 5 mg | $240.00 | ||
CX-5461 inhibits RNA Polymerase I, thereby affecting the synthesis of ribosomal RNA and potentially impacting proteins involved in RNA processing. | ||||||
Pladienolide B | 445493-23-2 | sc-391691 sc-391691B sc-391691A sc-391691C sc-391691D sc-391691E | 0.5 mg 10 mg 20 mg 50 mg 100 mg 5 mg | $290.00 $5572.00 $10815.00 $25000.00 $65000.00 $2781.00 | 63 | |
Pladienolide B targets the spliceosome, influencing RNA splicing. By affecting splicing, it could alter the processing of RNAs associated with RBMY1. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
5,6-Dichlorobenzimidazole riboside (DRB) is a kinase inhibitor that can inhibit RNA polymerase II, thus affecting transcription and potentially impacting RBMY1's function in processing RNA. | ||||||
Isoquinoline | 119-65-3 | sc-255224 sc-255224A | 5 g 100 g | $26.00 $58.00 | ||
Isoquinoline-1,3(2H,4H)-dione derivatives are known to bind RNA. Their interaction with RNA can potentially influence RNA-binding proteins like RBMY1. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA, inhibiting RNA polymerase and affecting RNA synthesis, which could indirectly influence RNA-binding proteins. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide is a diterpene triepoxide that inhibits RNA polymerase II. By doing so, it could indirectly affect proteins like RBMY1 that are associated with RNA. | ||||||