RBM38 Activators
RBM38 activators, as a class of compounds, are characterized by their potential to indirectly promote RBM38's expression or function through the modulation of various biochemical and cellular pathways. These activators include agents that alter the epigenetic landscape, such as histone deacetylase inhibitors (e.g., Trichostatin A, Vorinostat, Phenylbutyrate, Sodium butyrate), which may enhance the transcription of RBM38 by increasing chromatin accessibility. Epigenetic modifiers like DNA methyltransferase inhibitors (5-Azacytidine) can also lead to the upregulation of RBM38 by promoting gene demethylation and transcriptional activation.
In addition to epigenetic regulation, compounds that affect gene expression at the transcriptional level, such as retinoids and vitamin D3 analogs, can also serve as indirect activators. These compounds may bind to response elements in gene promoters and influence the transcription of genes including RBM38. Similarly, transcriptional modulators like actinomycin D and mithramycin A might influence RBM38 expression under certain cellular conditions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor that could lead to demethylation and activation of genes, potentially increasing RBM38 expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Influences gene expression and could upregulate RBM38 indirectly through retinoic acid-responsive elements in gene promoters. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
May enhance the expression of RBM38 by binding to vitamin D response elements in the promoter region of the gene encoding RBM38. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Interacts with DNA and can modulate gene expression, potentially increasing RBM38 levels under certain conditions. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
Antitumor antibiotic that binds to DNA and could affect the transcription of genes including those encoding RNA-binding proteins. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Histone deacetylase inhibitor that could induce hyperacetylation of histones, leading to increased expression of RBM38. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
HDAC inhibitor that may alter chromatin structure and enhance transcription of RBM38. | ||||||
Ellipticine | 519-23-3 | sc-200878 sc-200878A | 10 mg 50 mg | $145.00 $569.00 | 4 | |
Alkaloid that intercalates with DNA and can modulate transcription, potentially affecting RBM38 expression. | ||||||
Sodium phenylbutyrate | 1716-12-7 | sc-200652 sc-200652A sc-200652B sc-200652C sc-200652D | 1 g 10 g 100 g 1 kg 10 kg | $77.00 $166.00 $622.00 $5004.00 $32783.00 | 43 | |
HDAC inhibitor that can lead to increased gene expression and potentially upregulate RBM38. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Another HDAC inhibitor that could potentially increase the expression of RBM38 by altering chromatin accessibility. | ||||||