Rab 11A Activators

Common Rab 11A Activators include, but are not limited to SB 203580 CAS 152121-47-6, Genistein CAS 446-72-0, Resveratrol CAS 501-36-0, AICAR CAS 2627-69-2 and PGE2 CAS 363-24-6.

Rab11A activators are molecules or mechanisms that enhance the activity of Rab11A, a member of the Rab GTPase family. Rab11A is a crucial regulator of intracellular vesicular trafficking, particularly in the recycling endosomal pathway. These activators typically facilitate the exchange of GDP for GTP, which switches Rab11A into its active state. In this active form, Rab11A plays a pivotal role in coordinating the transport of vesicles loaded with cellular cargo, including proteins and lipids. It regulates the recycling endosomes, which are central hubs for sorting and delivering various components to their specific destinations within the cell.

Understanding the activation of Rab11A is fundamental to comprehending the intricacies of intracellular vesicular transport and its impact on cellular processes such as receptor recycling, cytokinesis, and cell polarity maintenance. Research into Rab11A activators provides insights into the regulation of these processes and can have implications for understanding cellular functions. In summary, Rab11A activators modulate Rab11A's activity, influencing intracellular vesicular trafficking and recycling pathways in eukaryotic cells.