Date published: 2025-9-13

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R3HDML Inhibitors

The "R3H domain containing like" protein, which can be abbreviated as R3HDL, is characterized by the presence of an R3H domain. The R3H domain is a conserved sequence motif found in a variety of proteins and is known to mediate protein-DNA, protein-RNA, or protein-protein interactions. Proteins with this domain are involved in a plethora of cellular processes, including but not limited to RNA binding, RNA metabolism, DNA repair, and gene regulation.This suggests a potential role for R3HDL in processes such as the regulation of mRNA stability, the modulation of transcription, and the maintenance of genome integrity. For example, R3H domain proteins may participate in the recognition and processing of mRNA precursors, or in the regulation of mRNA decay, thus influencing gene expression post-transcriptionally.Given the pivotal role of RNA in cellular function and the involvement of R3H domain proteins in RNA metabolism, mutations or dysregulation of R3HDL could potentially be implicated in a range of diseases, especially those related to aberrant gene expression.

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