PRDM12 inhibitors constitute a distinctive class of chemical compounds that have attracted scientific interest due to their potential to modulate the activity of PRDM12, also known as PR domain containing 12. PRDM12 is a protein involved in neural development and function, making it an intriguing target for research aimed at unraveling the intricate molecular mechanisms that govern these fundamental biological processes. These inhibitors encompass a diverse range of molecules, each characterized by unique structural attributes and mechanisms of action that enable them to interfere with PRDM12-mediated pathways. Structurally, PRDM12 inhibitors exhibit a broad spectrum of chemical scaffolds, spanning from small organic molecules to potential enzyme inhibitors. These compounds are designed to interact with specific binding sites or functional domains within the PRDM12 protein. Mechanistically, these inhibitors exert their effects through various routes. Some compounds may directly bind to PRDM12, potentially modulating its enzymatic activity and influencing gene expression programs related to neural development. Others might impact PRDM12 indirectly by altering its interactions with other cellular components and pathways involved in neural differentiation.
The study of PRDM12 inhibitors holds the promise of deepening our understanding of the intricate molecular mechanisms underlying neural development and function. Researchers delve into the structural conformation and functional properties of PRDM12, facilitating the design and optimization of inhibitors that can selectively target crucial regions of the protein. Furthermore, these inhibitors undergo meticulous biochemical and biophysical characterization to elucidate their modes of interaction with PRDM12 and to decipher how they perturb its function within the context of neural differentiation processes. The realm of PRDM12 inhibitors continues to evolve, with ongoing research contributing to novel insights into their mechanisms of action and potential applications. As our understanding of neural development deepens, the development and refinement of inhibitors within this class hold promise for expanding our comprehension of fundamental molecular events.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
GSK126 | 1346574-57-9 | sc-490133 sc-490133A sc-490133B | 1 mg 5 mg 10 mg | $90.00 $238.00 $300.00 | ||
GSK126 is a small molecule inhibitor that has been investigated for its potential to inhibit PRDMIts impact on PRDM12-mediated neuronal development processes could have implications for neural differentiation. | ||||||
UNC0638 | 1255580-76-7 | sc-397012 | 10 mg | $315.00 | ||
UNC0638 is a compound that inhibits the activity of histone methyltransferases, including PRDMIts mechanism of action involves modulating the epigenetic landscape and gene expression related to neuronal development. | ||||||
JIB 04 | 199596-05-9 | sc-397040 | 20 mg | $177.00 | ||
JIB-04 is a small molecule inhibitor that targets histone demethylases, including PRDMIts effects on the epigenetic regulation of gene expression might influence neural development processes. | ||||||
SP2509 | 1423715-09-6 | sc-492604 | 5 mg | $284.00 | ||
SP2509 is a compound that has been studied for its potential to inhibit PRDMIts mechanism of action could involve interfering with PRDM12-mediated neuronal differentiation pathways. | ||||||
Chaetocin | 28097-03-2 | sc-200893 | 200 µg | $120.00 | 5 | |
Chaetocin is a fungal metabolite that inhibits histone methyltransferases, including PRDMIts impact on the epigenetic regulation of gene expression might affect neural differentiation processes. | ||||||
EPZ6438 | 1403254-99-8 | sc-507456 | 1 mg | $66.00 | ||
EPZ-6438, also known as tazemetostat, is an inhibitor of histone methyltransferases. It has been investigated for its potential effects on PRDM12 and its implications for neuronal development. | ||||||
GSK343 | 1346704-33-3 | sc-397025 sc-397025A | 5 mg 25 mg | $148.00 $452.00 | 1 | |
GSK343 is a compound that targets histone methyltransferases, including PRDMIts mechanism of action involves modulating the epigenetic landscape and gene expression relevant to neural differentiation. | ||||||